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Submit ReviewIpratropium bromide
Description: Muscarinic antagonist
Chemical Name: (endo,syn)-(±)-3-(3-Hydroxy-1-oxo-2-phenylpropoxy)-8-methyl-8-(1-methylethyl)-8-azoniabicyclo[3.2.1]octane bromide
Purity: ≥98% (HPLC)
Biological Activity for Ipratropium bromide
Ipratropium bromide is a muscarinic antagonist, bronchodilator. N-Isopropyl salt of atropine.
Technical Data for Ipratropium bromide
| M. Wt | 412.37 |
| Formula | C20H30BrNO3 |
| Storage | Store at +4°C |
| Purity | ≥98% (HPLC) |
| CAS Number | 22254-24-6 |
| PubChem ID | 31098 |
| InChI Key | LHLMOSXCXGLMMN-UHFFFAOYSA-M |
| Smiles | O=C(C(CO)C3=CC=CC=C3)O[C@@H]1CC2CCC([N+](C)2C(C)C)C1.[Br-] |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Ipratropium bromide
References for Ipratropium bromide
References are publications that support the biological activity of the product.
Fryer and Maclagan (1987) Ipratropium bromide potentiates bronchoconstriction induced by vagal nerve stimulation in the guinea-pig. Eur.J.Pharmacol. 139 187 PMID: 2958300
Merck Index 12 5089
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Keywords: Ipratropium bromide, Ipratropium bromide supplier, Muscarinic, antagonists, Receptors, Acetylcholine, bronchodilator, ACh, Non-selective, Muscarinics, 0692, Tocris Bioscience
3 Citations for Ipratropium bromide
Citations are publications that use Tocris products. Selected citations for Ipratropium bromide include:
Valeria et al (2016) A subnanomolar concentration of Pituitary Adenylate Cyclase Activating Polypeptide (PACAP) pre-synaptically modulates glutamatergic transmission in the rat hippocampus acting through acetylcholine Neuroscience 340 551 PMID: 27816700
Deng et al (2013) Label-free cell phenotypic assessment of the biased agonism and efficacy of agonists at the endogenous muscarinic M3 receptors. J Pharmacol Toxicol Methods 68 323 PMID: 23933114
Woo et al (2007) Neuregulin-1 enhances depolarization-induced GABA release. Neuron 54 599 PMID: 17521572
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