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Submit ReviewL-695,845
Description: High affinity s ligand
Chemical Name: 3,4-Dihydro-1'-(3-methylbut-2-enyl)spiro[1H-indene-1,4'-piperidine]
Biological Activity for L-695,845
High affinity σ ligand with 10000-fold preference for theσ binding site over the dopamine D2 receptor.
Licensing Information
Sold with the permission of Merck Sharp & Dohme Ltd.
Technical Data for L-695,845
| M. Wt | 255.4 |
| Storage | Desiccate at -20°C |
| CAS Number | 137730-58-6 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for L-695,845
Certificate of Analysis is currently unavailable on-line.
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References for L-695,845
References are publications that support the biological activity of the product.
Chambers et al (1992) Spiropiperidines as high affinity, selective σ ligands. J.Med.Chem. 35 2033 PMID: 1317923
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Keywords: L-695,845, L-695,845 supplier, Sigma-Related, 0473, Tocris Bioscience
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