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Submit ReviewL-Dehydroascorbic acid
Description: GLUT1 substrate; oxidized form of L-Ascorbic acid
Chemical Name: L-threo-2,3-Hexodiulosonic acid γ-lactone
Biological Activity for L-Dehydroascorbic acid
L-Dehydroascorbic acid is a oxidized form of L-Ascorbic acid (Cat. No. 4055). Transported into cells through GLUT1. Selectively induces cell death in KRAS and BRAF mutant cells in vitro.
Technical Data for L-Dehydroascorbic acid
| M. Wt | 174.11 |
| Formula | C6H6O6 |
| Storage | Store at -20°C |
| CAS Number | 490-83-5 |
| PubChem ID | 440667 |
| InChI Key | SBJKKFFYIZUCET-JLAZNSOCSA-N |
| Smiles | O=C1C([C@]([C@@H](O)CO)([H])OC1=O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for L-Dehydroascorbic acid
References for L-Dehydroascorbic acid
References are publications that support the biological activity of the product.
Kaiser (2015) Vitamin C could target some common cancers. Science 6 6261 PMID: 26542550
Yun et al (2015) Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH. Science 11 6266 PMID: 26541605
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Keywords: L-Dehydroascorbic acid, L-Dehydroascorbic acid supplier, vitamin, vit, C, oxidised, form, L-Ascorbic, acid, GLUT1, glucose, transporters, KRAS, BRAF, Glucose, Transporters, Antioxidants, 5734, Tocris Bioscience
Citations for L-Dehydroascorbic acid
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Currently there are no citations for L-Dehydroascorbic acid.
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