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Submit ReviewLinomide
Description: Immunomodulator with antiangiogenic properties
Chemical Name: 1,2-Dihydro-4-hydroxy-N,N-dimethyl-2-oxo-N-phenyl-3-quinolinecarboxamide
Purity: ≥99% (HPLC)
Biological Activity for Linomide
Linomide is an immunomodulator with stimulatory and antitumor properties. Inhibits in vivo apoptosis of T cells and inhibits angiogenesis in rats in vivo.
Technical Data for Linomide
| M. Wt | 308.33 |
| Formula | C18H16N2O3 |
| Storage | Store at RT |
| Purity | ≥99% (HPLC) |
| CAS Number | 84088-42-6 |
| PubChem ID | 54676478 |
| InChI Key | SGOOQMRIPALTEL-UHFFFAOYSA-N |
| Smiles | CN(C(=O)C1=C(O)C2=CC=CC=C2N(C)C1=O)C1=CC=CC=C1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Linomide
References for Linomide
References are publications that support the biological activity of the product.
Gonzalo et al (1994) Linomide inhibits programmed cell death of peripheral T cells in vivo. Eur.J.Immunol. 24 48 PMID: 8020570
Ichikawa et al (1992) The antitumor effects of the quinoline-3-carboxamide linomide on Dunning R-3327 rat prostatic cancers. Cancer Res. 52 3022 PMID: 1591718
Vukanovic et al (1993) Antiangiogenic effects of the quinoline-3-carboxamide linomide. Cancer Res. 53 1833 PMID: 7682157
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Keywords: Linomide, Linomide supplier, Immunomodulators, antiangiogenics, Antiangiogenics, 1461, Tocris Bioscience
Citations for Linomide
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Currently there are no citations for Linomide.
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Literature in this Area
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Angiogenesis in Cancer Poster
This poster summarizes the pathogenesis of angiogenesis in cancer, as well as some of the main angiogenesis therapeutic targets.