Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewMastoparan
Discontinued Product
1192 has been discontinued.
View all Heterotrimeric G-protein GTPases products.
Description: Activates Gi and Go
Biological Activity for Mastoparan
Mastoparan is a peptide activator of Gi and Go.
Technical Data for Mastoparan
| M. Wt | 1479 |
| Formula | C70H131N19O15 |
| Sequence |
INLKALAALAKKIL (Modifications: Leu-14 = C-terminal amide) |
| Storage | Desiccate at -20°C |
| CAS Number | 72093-21-1 |
| PubChem ID | 6324633 |
| InChI Key | MASXKPLGZRMBJF-MVSGICTGSA-N |
| Smiles | [H]N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(N)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Mastoparan
References for Mastoparan
References are publications that support the biological activity of the product.
Higashijima and Ros (1991) Mapping of the mastoparan-binding site on G proteins. Cross-linking of [125I-Tyr3,Cys11]mastoparan to Go. J.Biol.Chem. 266 12655 PMID: 1905730
Longland et al (1999) The mechanism of inhibition of the Ca2+-ATPase by mastoparan. J.Biol.Chem. 274 14799 PMID: 10329678
Mousli et al (1990) G protein activation: a receptor-independent mode of action for cationic amphiphilic neuropeptides and venom peptides. TiPS 11 358 PMID: 2122563
Raynor et al (1991) Membrane interactions of amphiphilic polypeptides mastoparan, melittin, plymixin B and cardiotoxin. J.Biol.Chem. 266 2753 PMID: 1847132
View Related Products by Target
View Related Products by Product Action
Keywords: Mastoparan, Mastoparan supplier, Activator, Gi, Go, Gi/o, G-Protein, Signaling, Signalling, Heterotrimeric, G-protein, GTPases, 1192, Tocris Bioscience
1 Citation for Mastoparan
Citations are publications that use Tocris products. Selected citations for Mastoparan include:
Akoume et al (2019) A Differential Hypofunctionality of Gαi Proteins Occurs in Adolescent Idiopathic Scoliosis and Correlates with the Risk of Disease Progression. Sci Rep 9 10074 PMID: 31296888
Reviews for Mastoparan
There are currently no reviews for this product. Be the first to review Mastoparan and earn rewards!
Have you used Mastoparan?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image