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Submit Review(-)-5'-DMH-CBD
Description: Metabolically stable anandamide transport inhibitor
Alternative Names: (-)-5'-Dimethylheptyl-cannabidiol
Chemical Name: 5-(1,1-Dimethylheptyl)-2-[(1R,6R)-3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]-1,3-benzenediol
Biological Activity for (-)-5'-DMH-CBD
(-)-5'-DMH-CBD is an anandamide membrane transport inhibitor (IC50 = 14 μM) that is relatively metabolically stable. Displays some affinity for CB2 receptors but has only weak affinity for CB1 receptors and has no activity at VR1 receptors or FAAH. Anticonvulsive in vivo following systemic administration.
Technical Data for (-)-5'-DMH-CBD
| M. Wt | 370.57 |
| Formula | C25H38O2 |
| Storage | Desiccate at -20°C |
| CAS Number | 97452-63-6 |
| PubChem ID | 126670 |
| InChI Key | MPJURNPNPDQYSY-LEWJYISDSA-N |
| Smiles | C=[C@](C)[C@@H]1CCC(C)=C[C@H]1[C@]2=C(O)C=C(C(C)(C)CCCCCC)C=C2O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for (-)-5'-DMH-CBD
References for (-)-5'-DMH-CBD
References are publications that support the biological activity of the product.
Bisogno et al (2001) Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide. Br.J.Pharmacol. 134 845 PMID: 11606325
Leite et al (1982) Anticonvulsant effects of the (-) and (+)isomers of cannabidiol and their dimethylheptyl homologs. Pharmacology 24 141 PMID: 7071126
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Keywords: (-)-5'-DMH-CBD, (-)-5'-DMH-CBD supplier, Metabolically, stable, anandamide, transporters, inhibitors, inhibits, AMT, Anandamide, Cannabinoids, Monoamine, Neurotransmitter, (-)-5-DMH-CBD, cannabidiol, (-)-5'-Dimethylheptyl-cannabidiol, Cannabinoid, Transporters, 1481, Tocris Bioscience
Citations for (-)-5'-DMH-CBD
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