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Description: Caged D-aspartate; NMDA agonist
Alternative Names: 4-Methoxy-7-nitroindolinyl-caged-D-aspartate
Chemical Name: (R)-α-Amino-2,3-dihydro-4-methoxy-7-nitro-γ-oxo-1H-indole-1-butanoic acid
Purity: ≥98% (HPLC)
Biological Activity for MNI-caged-D-aspartate
MNI-caged-D-aspartate is a D-aspartate caged with the photosensitive 4-methoxy-7-nitroindolinyl group. Photolyzed by UV light with a quantum efficiency of 0.09 at pH 7.4. Agonist at NMDA receptors and EAAT substrate.
Licensing Information
Sold under license from the UK Medical Research Council
Technical Data for MNI-caged-D-aspartate
| M. Wt | 309.27 |
| Formula | C13H15N3O6 |
| Storage | Store at -20°C |
| Purity | ≥98% (HPLC) |
| CAS Number | 845555-94-4 |
| PubChem ID | 56972233 |
| InChI Key | ATNVWKDWOLQDKH-MRVPVSSYSA-N |
| Smiles | O=C(C[C@H](C(O)=O)N)N2C1=C([N+]([O-])=O)C=CC(OC)=C1CC2 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for MNI-caged-D-aspartate
References for MNI-caged-D-aspartate
References are publications that support the biological activity of the product.
Huang et al (2005) Synthesis and characterization of 4-methoxy-7-nitroindolinyl-D-aspartate, a caged compound for selective activation of glutamate transporters and N-MthD.-aspartate receptors in brain tissue. Biochemistry 44 3316 PMID: 15736942
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Keywords: MNI-caged-D-aspartate, MNI-caged-D-aspartate supplier, MNI-caged-D-aspartate, NMDA, agonists, Glutamate, Receptors, N-Methyl-D-Aspartate, iGluR, Ionotropic, Caged, Compounds, EAAT, excitatory, amino, acid, transporters, 4-Methoxy-7-nitroindolinyl-caged-D-aspartate, Transporters, 2277, Tocris Bioscience
Citations for MNI-caged-D-aspartate
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