MNQX

Discontinued Product

0277 has been discontinued.

View all NMDA Receptors products.
Description: Potent NMDA antagonist, acts glycine site
Chemical Name: 5,7-Dinitroquinoxaline-2,3-dione
Datasheet
Citations
Reviews
Literature (5)

Biological Activity for MNQX

NMDA/glycine site antagonist, more potent than the structurally related CNQX. Also an AMPA/kainate antagonist, less potent than CNQX.

Technical Data for MNQX

M. Wt 252.14
Storage Store at RT
CAS Number 125910-83-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for MNQX

Certificate of Analysis is currently unavailable on-line.
Please contact Customer Service

References for MNQX

References are publications that support the biological activity of the product.

Sheardown et al (1989) A potent antagonist of the strychnine insensitive glycine receptor has anticonvulsant properties. Eur.J.Pharmacol. 174 197 PMID: 2560979

Watkins et al (1990) Structure-activity relationships in the development of excitatory amino acid receptor agonists and competitive antagonists. TiPS 11 25 PMID: 2155495

View Related Products by Target

View Related Products by Product Action

View all NMDA Receptor Antagonists

Keywords: MNQX, MNQX supplier, NMDA, Receptors, 0277, Tocris Bioscience

Citations for MNQX

Citations are publications that use Tocris products.

Currently there are no citations for MNQX.

Reviews for MNQX

There are currently no reviews for this product. Be the first to review MNQX and earn rewards!

Have you used MNQX?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


Huntington's Disease Research Product Guide

Huntington's Disease Research Product Guide

This product guide provides a background to Huntington's disease research and lists around 100 products for the study of:

  • Somatic Instability
  • Proteolysis and Inclusion Bodies
  • Transcriptional Dysregulation
  • Mitochondrial Dysfunction
  • Nuclear-Cytoplasmic Transport Interference
  • Excitotoxicity
  • Stem Cells
Alzheimer's Disease Poster

Alzheimer's Disease Poster

Alzheimer's disease (AD) is a debilitating and progressive neurodegenerative disease and the most common cause of dementia, affecting approximately 30% of individuals aged over 85 years. This poster summarizes the cellular and molecular mechanisms of AD.

Depression Poster

Depression Poster

Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.

Huntington's Disease Poster

Huntington's Disease Poster

Huntington's disease (HD) is a severe monogenic neurodegenerative disorder, which is characterized by the prevalent loss of GABAergic medium spiny neurons (MSN) in the striatum. This poster summarizes the effects of mutant huntingtin aggregation implicated in the pathology of HD, as well as highlighting the use of iPSCs for HD modeling.

Parkinson's Disease Poster

Parkinson's Disease Poster

Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.