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Submit ReviewN-Acetylglycyl-D-glutamic acid is an excitatory peptide, more potent than L-glutamic acid at inducing seizures in mice.
M. Wt | 246.22 |
Formula | C9H14N2O6 |
Storage | Store at RT |
CAS Number | 135701-69-8 |
PubChem ID | 6604718 |
InChI Key | CQTYJLQESPLSOP-ZCFIWIBFSA-N |
Smiles | CC(=O)NCC(=O)N[C@H](CCC(O)=O)C(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Garyaev et al (1991) Excitatory action of some aspartate- and glutamate-containing dipeptides after intracerebroventricular injection in mice. Eur.J.Pharmacol. 197 157 PMID: 1655472
Keywords: N-Acetylglycyl-D-glutamic acid, N-Acetylglycyl-D-glutamic acid supplier, Potent, convulsant, Glutamate, mGlur, Receptors, Metabotropic, iGluR, Ionotropic, agonists, Acetylglycylglutamic, Miscellaneous, 0395, Tocris Bioscience
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Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.
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