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Submit ReviewNPEC-caged-D-AP5
Description: Caged D-AP5 (Cat.No. 0106)
Chemical Name: D-[[1-(2-Nitrophenyl)ethyl]carbamoyl]-2-amino]-5-phosphonopentanoic acid
Purity: ≥99% (HPLC)
Biological Activity for NPEC-caged-D-AP5
NPEC-caged-D-AP5 is a D-AP5 (Cat.No. 0106) caged with the photosensitive 1-(2-nitrophenyl)ethoxycarbonyl (NPEC) group. NMDA receptor antagonist.
Technical Data for NPEC-caged-D-AP5
| M. Wt | 390.28 |
| Formula | C14H19N2O9P |
| Storage | Store at -20°C |
| Purity | ≥99% (HPLC) |
| CAS Number | 1416943-27-5 |
| PubChem ID | 90488920 |
| InChI Key | RLEANJAZNZWLHC-HCCKASOXSA-N |
| Smiles | O=C(OC(C)C1=CC=CC=C1[N+]([O-])=O)N[C@H](CCCP(O)(O)=O)C(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for NPEC-caged-D-AP5
References for NPEC-caged-D-AP5
References are publications that support the biological activity of the product.
Murphy et al (1997) Activation of NMDA receptors is necessary for the induction of associative long-term potentiation in area CA1 of the rat hippocampal slice. J.Physiol. 504 379 PMID: 9365912
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Citations for NPEC-caged-D-AP5
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Metabotropic Glutamate Receptors Scientific Review
Written by Francine Acher, this review discusses the pharmacology and therapeutic potential of mGlu receptors, and the compounds acting upon them; compounds available from Tocris are listed.
Depression Poster
Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.
Parkinson's Disease Poster
Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.