Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewO4I1
Description: Oct3/4 inducer
Chemical Name: 4-[(4-Methoxyphenyl)methoxy]benzeneacetonitrile
Purity: ≥99% (HPLC)
Biological Activity for O4I1
Oct3/4 inducer. Increases Oct3/4 mRNA levels in HEK293 cells by 2.5- and 4-fold at 10 μM and 20 μM, respectively. Also increases expression of Oct3/4 in human adult and neonatal fibroblasts.
Technical Data for O4I1
| M. Wt | 253.3 |
| Formula | C16H15NO2 |
| Storage | Store at RT |
| Purity | ≥99% (HPLC) |
| CAS Number | 175135-47-4 |
| PubChem ID | 2774690 |
| InChI Key | QJEJLARVLKHYFW-UHFFFAOYSA-N |
| Smiles | N#CCC1=CC=C(OCC2=CC=C(OC)C=C2)C=C1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for O4I1
References for O4I1
References are publications that support the biological activity of the product.
Cheng et al (2015) Identification of 2-[4-[(4-Methoxyphenyl)methoxy]-phenyl]acetonitrile and derivatives as potent Oct3/4 inducers. J.Med.Chem. 58 4976 PMID: 25898186
View Related Products by Target
Keywords: O4I1, O4I1 supplier, induced, pluripotent, stem, cell, iPSCs, dedifferentiation, inducers, Oct3/4, reprogramming, Stem, Cell, Reprogramming, Other, Transcription, Factors, 5639, Tocris Bioscience
Citations for O4I1
Citations are publications that use Tocris products.
Currently there are no citations for O4I1.
Reviews for O4I1
There are currently no reviews for this product. Be the first to review O4I1 and earn rewards!
Have you used O4I1?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Stem Cell Research Product Guide
This product guide provides a background to the use of small molecules in stem cell research and lists over 200 products for use in:
- Self-renewal and Maintenance
- Differentiation
- Reprogramming
- Organoid Generation
- GMP and Ancillary Material Grade Products
Stem Cells Scientific Review
Written by Kirsty E. Clarke, Victoria B. Christie, Andy Whiting and Stefan A. Przyborski, this review provides an overview of the use of small molecules in the control of stem cell growth and differentiation. Key signaling pathways are highlighted, and the regulation of ES cell self-renewal and somatic cell reprogramming is discussed. Compounds available from Tocris are listed.
Stem Cell Workflow Poster
Stem cells have potential as a source of cells and tissues for research and treatment of disease. This poster summarizes some key protocols demonstrating the use of small molecules across the stem cell workflow, from reprogramming, through self-renewal, storage and differentiation to verification. Advantages of using small molecules are also highlighted.
Stem Cells Poster
Written by Rebecca Quelch and Stefan Przyborski from Durham University (UK), this poster describes the isolation of pluripotent stem cells, their maintenance in culture, differentiation, and the generation and potential uses of organoids.