PDD 00031705

Discontinued Product

7009 has been discontinued.

View all Poly(ADP-ribose) Glycohydrolase products.
Description: Negative control for PDD 00017238 (Cat. No. 7007)
Chemical Name: 1-[(2,4-Dimethyl-5-thiazolyl)methyl]-2,3-dihydro-N-methyl-N-(1-methylcyclopropyl)-2-oxo-3-(1,2,4-thiadiazol-5-yl)-1H-benzimidazole-5-sulfonamide
Purity: ≥98% (HPLC)
Datasheet
Citations (1)
Reviews
Literature (1)

Biological Activity for PDD 00031705

PDD 00031705 is a negative control for PDD 00017238 (Cat. No. 7007).

Technical Data for PDD 00031705

M. Wt 490.62
Formula C20H22N6O3S3
Storage Store at -20°C
Purity ≥98% (HPLC)
CAS Number 2032096-45-8
PubChem ID 123131658
InChI Key KWGUETFSHQZXMA-UHFFFAOYSA-N
Smiles CN(S(=O)(C1=CC=C2N(C(N(C2=C1)C3=NC=NS3)=O)CC4=C(N=C(S4)C)C)=O)C5(CC5)C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

References for PDD 00031705

References are publications that support the biological activity of the product.

James et al (2016) First-in-class chemical probes against poly(ADP-ribose) glycohydrolase (PARG) inhibit DNA repair with differential pharmacology to Olaparib. ACS Chem.Biol. 11 3179 PMID: 27689388

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Keywords: PDD 00031705, PDD 00031705 supplier, PDD00031705, poly, ADP, ribose, glycohydrolase, PARG, inhibitors, negative, controls, Poly(ADP)-ribose, Glycohydrolase, 7009, Tocris Bioscience

1 Citation for PDD 00031705

Citations are publications that use Tocris products. Selected citations for PDD 00031705 include:

Craig A et al (2018) Hypoxia induces pulmonary fibroblast proliferation through NFAT signaling. Sci Rep 8 2709 PMID: 29426911


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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


Epigenetics in Cancer Poster

Epigenetics in Cancer Poster

This poster summarizes the main epigenetic targets in cancer. The dysregulation of epigenetic modifications has been shown to result in oncogenesis and cancer progression. Unlike genetic mutations, epigenetic alterations are considered to be reversible and thus make promising therapeutic targets.