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Submit ReviewPF 750
Description: Selective FAAH inhibitor
Chemical Name: N-Phenyl-4-(3-quinolinylmethyl)-1-piperidinecarboxamide
Purity: ≥98% (HPLC)
Biological Activity for PF 750
PF 750 is an irreversible fatty acid amide hydrolase (FAAH) inhibitor (IC50 = 16.2 nM) that displays no activity at a range of other serine hydrolases. Selectively inhibits FAAH within the central nervous system. Orally active.
Technical Data for PF 750
| M. Wt | 345.44 |
| Formula | C22H23N3O |
| Storage | Store at RT |
| Purity | ≥98% (HPLC) |
| CAS Number | 959151-50-9 |
| PubChem ID | 25154868 |
| InChI Key | BIODYGOZWZNCAG-UHFFFAOYSA-N |
| Smiles | O=C(NC4=CC=CC=C4)N(CC3)CCC3CC2=CC1=CC=CC=C1N=C2 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for PF 750
References for PF 750
References are publications that support the biological activity of the product.
Ahn et al (2007) Novel mechanistic class of fatty acid amide hydrolase inhibitors with remarkable selectivity. Biochemistry 46 13019 PMID: 17949010
Mileni et al (2008) Structure-guided inhibitor design for human FAAH by interspecies active site conversion. Proc.Natl.Acad.Sci.USA 105 12820
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Citations for PF 750
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Currently there are no citations for PF 750.
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
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