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(R)-(+)-Propranolol hydrochloride

Cat. No. 0835 Submit a Review Datasheet / COA / SDS
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Description: β antagonist. Less active enantiomer of propranolol (Cat. No. 0624)
Chemical Name: (R)-(+)-1-[(1-methylethyl)amino]-3-(1-naphthalenyloxy)-2-propanol hydrochloride
Datasheet
Citations
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Literature (1)
Biological Activity Technical Data Solubility Calculators Datasheets References

Biological Activity for (R)-(+)-Propranolol hydrochloride

(R)-(+)-Propranolol hydrochloride is a less active enantiomer of the β-adrenoceptor antagonist propranolol.

Racemate, S-enantiomer and Glycol Metabolite also available.

Technical Data for (R)-(+)-Propranolol hydrochloride

M. Wt 295.81
Formula C16H21NO2.HCl
Storage Store at RT
CAS Number 13071-11-9
PubChem ID 66366
InChI Key ZMRUPTIKESYGQW-PFEQFJNWSA-N
Smiles CC(C)NC[C@@]([H])(O)COC2=CC=CC1=CC=CC=C12.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for (R)-(+)-Propranolol hydrochloride

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 100

Preparing Stock Solutions for (R)-(+)-Propranolol hydrochloride

The following data is based on the product molecular weight 295.81. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.38 mL 16.9 mL 33.81 mL
5 mM 0.68 mL 3.38 mL 6.76 mL
10 mM 0.34 mL 1.69 mL 3.38 mL
50 mM 0.07 mL 0.34 mL 0.68 mL

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Reconstitution Calculator

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Product Datasheets for (R)-(+)-Propranolol hydrochloride

Certificate of Analysis / Product Datasheet
Safety Datasheet

References for (R)-(+)-Propranolol hydrochloride

References are publications that support the biological activity of the product.

Barrett et al (1968) The biological properties of the optical isomers of propra. and their effects on cardiac arrhythmias. Br.J.Pharmacol. 34 43 PMID: 19108278

Bond et al (1967) Metabolism of propra. (Inderal) a potent, specific β-adrenergic receptor blocking agent. Nature 213 721 PMID: 6031788

If you know of a relevant reference for (R)-(+)-Propranolol hydrochloride, please let us know.

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Citations for (R)-(+)-Propranolol hydrochloride

Citations are publications that use Tocris products.

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

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Depression Poster

Depression Poster

Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.