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Submit ReviewTrace amine 1 (TA1) receptor agonist; increases chloride conductance in oocytes coexpressing hCFTR and mouse TA1 receptors.
M. Wt | 337.84 |
Formula | C18H23NO3.HCl |
Storage | Desiccate at RT |
Purity | ≥97% (HPLC) |
CAS Number | 90274-24-1 |
PubChem ID | 14010333 |
InChI Key | JHGSLSLUFMZUMK-UHFFFAOYSA-N |
Smiles | OC1=CC=C(C(O)CNC(CCC2=CC=C(O)C=C2)C)C=C1.Cl |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Liu et al (2014) Ractopamine, a livestock feed additive, is a full agonist at trace amine-associated receptor 1. J.Pharmacol.Exp.Ther. 350 124 PMID: 24799633
Keywords: Ractopamine hydrochloride, Ractopamine hydrochloride supplier, Trace, amine, 1, TA1, receptors, agonists, agonism, chloride, conductance, TAAR, Amine, Receptor, 5252, Tocris Bioscience
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Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
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Written by Phillip Strange and revised by Kim Neve in 2013, this review summarizes the history of the dopamine receptors and provides an overview of individual receptor subtype properties, their distribution and identifies ligands which act at each receptor subtype. Compounds available from Tocris are listed.
Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.