Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewRepSox
Description: RepSox synthesized to Ancillary Material Grade
Alternative Names: ALK5 Inhibitor II,SJN 2511,E-616452
Chemical Name: 2-[3-(6-Methylpyridin-2-yl)-1H-pyrazol-4-yl]-1,5-naphthyridine
Purity: ≥99%
Biological Activity for RepSox
RepSox is an ancillary Material Grade version of product RepSox (Cat. No. 3742). Suitable for use as an ancillary reagent in the further manufacturing of cell therapies.
Find out more about our Ancillary Material Grade product range.
Technical Data for RepSox
| M. Wt | 287.32 |
| Formula | C17H13N5 |
| Storage | Store at 2-8°C |
| Purity | ≥99% |
| CAS Number | 446859-33-2 |
| InChI Key | LBPKYPYHDKKRFS-UHFFFAOYSA-N |
| Smiles | CC1=NC(C2=NNC=C2C3=NC4=CC=CN=C4C=C3)=CC=C1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for RepSox
Certificate of Analysis is currently unavailable on-line.
Please contact Customer Service
Please contact Customer Service
References for RepSox
References are publications that support the biological activity of the product.
If you know of a relevant reference for RepSox, please let us know.
View Related Products by Target
Keywords: RepSox, RepSox supplier, Ancillary, Material, Grade, potent, inhibitors, inhibits, TGF-betaRI, TGF-beta, TGFbRI, TGFbR1, tgf-b1, ALK5, Transforming,Growth, Factors, Beta, stem, cells, E-616452, SJN2511, SJN, 2511, Stem, Cell, Reprogramming, manufacturing, gene, cell, therapies, GMP, Inhibitor, II, Small, Molecules, TB3742-RMU, Tocris Bioscience
1 Citation for RepSox
Citations are publications that use Tocris products. Selected citations for RepSox include:
Mishra et al (2022) Improved loss-of-function CRISPR-Cas9 genome editing in human cells concomitant with inhibition of TGF-beta signaling. Mol.Ther.Nucleic Acids 28 202 PMID: 35402072
Do you know of a great paper that uses RepSox from Tocris? Please let us know.
Reviews for RepSox
There are currently no reviews for this product. Be the first to review RepSox and earn rewards!
Have you used RepSox?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Stem Cell Research Product Guide
This product guide provides a background to the use of small molecules in stem cell research and lists over 200 products for use in:
- Self-renewal and Maintenance
- Differentiation
- Reprogramming
- Organoid Generation
- GMP and Ancillary Material Grade Products
Stem Cells Scientific Review
Written by Kirsty E. Clarke, Victoria B. Christie, Andy Whiting and Stefan A. Przyborski, this review provides an overview of the use of small molecules in the control of stem cell growth and differentiation. Key signaling pathways are highlighted, and the regulation of ES cell self-renewal and somatic cell reprogramming is discussed. Compounds available from Tocris are listed.
Stem Cell Workflow Poster
Stem cells have potential as a source of cells and tissues for research and treatment of disease. This poster summarizes some key protocols demonstrating the use of small molecules across the stem cell workflow, from reprogramming, through self-renewal, storage and differentiation to verification. Advantages of using small molecules are also highlighted.
Stem Cells Poster
Written by Rebecca Quelch and Stefan Przyborski from Durham University (UK), this poster describes the isolation of pluripotent stem cells, their maintenance in culture, differentiation, and the generation and potential uses of organoids.