(RS)-3,4-DCPG

Discontinued Product

1394 has been discontinued.

View all Non-selective Ionotropic Glutamate products.
Description: Potent systemically active anticonvulsant. Racemate of (R)-3,4,-DCPG (Cat. No. 1395)
Chemical Name: (RS)-3,4-Dicarboxyphenylglycine
Purity: ≥99% (HPLC)
Datasheet
Citations (1)
Reviews
Literature (1)

Biological Activity for (RS)-3,4-DCPG

(RS)-3,4-DCPG is a systemically active anticonvulsant that is 30-100-fold more potent in vivo than the separate enantiomers (S)-3,4-DCPG or (R)-3,4,-DCPG.

S-enantiomer and R-enantiomer also available.

Technical Data for (RS)-3,4-DCPG

M. Wt 239.18
Formula C10H9NO6
Storage Desiccate at RT
Purity ≥99% (HPLC)
CAS Number 176796-64-8
PubChem ID 3313698
InChI Key IJVMOGKBEVRBPP-UHFFFAOYSA-N
Smiles NC(C(O)=O)C1=CC=C(C(O)=O)C(=C1)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for (RS)-3,4-DCPG

Certificate of Analysis / Product Datasheet
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References for (RS)-3,4-DCPG

References are publications that support the biological activity of the product.

Moldrich et al (2001) Anticonvulsant activity of 3,4-dicarboxyphenylglycines in DBA/2 mice. Neuropharmacology 40 732 PMID: 11311902

Thomas et al (1997) Dicarboxyphenylglycines antagonize AMPA- but not kainate-induced depolarizations in neonatal rat motoneurones. Eur.J.Pharmacol. 338 111 PMID: 9455991

Thomas et al (1998) Pharmacological differentiation of kainate receptors on neonatal rat spinal motoneurones and dorsal roots. Neuropharmacology 37 1223 PMID: 9849660

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Keywords: (RS)-3,4-DCPG, (RS)-3,4-DCPG supplier, Potent, systemically, active, anticonvulsant, Racemate, Glutamate, Ionotropic, Non-Selective, iGlur, Receptors, Group, III, mGluR8, mGlu8, Metabotropic, antagonists, Non-selective, (Metabotropic), 1394, Tocris Bioscience

1 Citation for (RS)-3,4-DCPG

Citations are publications that use Tocris products. Selected citations for (RS)-3,4-DCPG include:

Gosnell et al (2011) mGluR8 modulates excitatory transmission in the bed nucleus of the stria terminalis in a stress-dependent manner. Neuropsychopharmacology 36 1599 PMID: 21451497


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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

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