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Submit Review(RS)-(Tetrazol-5-yl)glycine
Description: Highly potent NMDA agonist
Purity: ≥98% (HPLC)
Biological Activity for (RS)-(Tetrazol-5-yl)glycine
(RS)-(Tetrazol-5-yl)glycine is a potent NMDA receptor agonist, approximately 20 times more active than NMDA.
Technical Data for (RS)-(Tetrazol-5-yl)glycine
| M. Wt | 143.1 |
| Formula | C3H5N5O2 |
| Storage | Store at RT |
| Purity | ≥98% (HPLC) |
| CAS Number | 138199-51-6 |
| PubChem ID | 126383 |
| InChI Key | UKBRUIZWQZHXFL-UHFFFAOYSA-N |
| Smiles | NC(C(O)=O)C1=NN=NN1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for (RS)-(Tetrazol-5-yl)glycine
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 50 |
Preparing Stock Solutions for (RS)-(Tetrazol-5-yl)glycine
The following data is based on the product molecular weight 143.1. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.5 mM | 13.98 mL | 69.88 mL | 139.76 mL |
| 2.5 mM | 2.8 mL | 13.98 mL | 27.95 mL |
| 5 mM | 1.4 mL | 6.99 mL | 13.98 mL |
| 25 mM | 0.28 mL | 1.4 mL | 2.8 mL |
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Product Datasheets for (RS)-(Tetrazol-5-yl)glycine
References for (RS)-(Tetrazol-5-yl)glycine
References are publications that support the biological activity of the product.
Arnt et al (1995) Diffentiation of in vivo effects of AMPA and NMDA receptor ligands using drug discrimination methods and convulsant/anticonvulsant activity. Eur.J.Pharmacol. 285 289 PMID: 8575516
Moroni et al (1995) NMDA receptor heterogeneity in mammalian tissues: focus on two agonists, (2S,3R,4S)cyclopropylglutamate and the sulfate ester of 4-hydroxy-(S)-pipecolic acid. Naunyn Schmiedebergs Arch.Pharmacol. 351 371 PMID: 7543185
Schoepp et al (1991) D,L-(Tetrazol-5-yl)glycine a novel and highly potent NMDA receptor agonist. Eur.J.Pharmacol. 203 237 PMID: 1686860
If you know of a relevant reference for (RS)-(Tetrazol-5-yl)glycine, please let us know.
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Citations for (RS)-(Tetrazol-5-yl)glycine
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