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Submit ReviewS 07662
Discontinued Product
5188 has been discontinued.
View all Constitutive Androstane Receptor products.
Description: Constitutive androstane receptor (CAR) inverse agonist
Chemical Name: N-[(2-Methyl-3-benzofuranyl)methyl]-N'-(2-thienylmethyl)urea
Purity: ≥98% (HPLC)
Biological Activity for S 07662
S 07662 is an inverse agonist of the constitutive androstane receptor (CAR). Inhibits CAR activity via recruitment of nuclear receptor co-repressor (NCoR). Suppresses CITCO-induced CYP2B6 gene expression in human primary hepatocytes.
Technical Data for S 07662
| M. Wt | 300.38 |
| Formula | C16H16N2O2S |
| Storage | Store at +4°C |
| Purity | ≥98% (HPLC) |
| CAS Number | 883226-64-0 |
| PubChem ID | 2732040 |
| InChI Key | UITFWLJMEZPXOF-UHFFFAOYSA-N |
| Smiles | CC2=C(CNC(NCC3=CC=CS3)=O)C1=CC=CC=C1O2 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for S 07662
References for S 07662
References are publications that support the biological activity of the product.
Küblbeck et al (2011) New in vitro tools to study human constitutive androstane receptor (CAR) biology: discovery and comparison of human CAR inverse agonists. Mol.Pharm. 8 2424 PMID: 22044162
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Keywords: S 07662, S 07662 supplier, S07662, inverse, agonists, constitutive, androstane, receptors, CAR, nuclear, Constitutive, Androstane, Receptor, 5188, Tocris Bioscience
Citations for S 07662
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