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Submit ReviewS-Isopropylisothiourea hydrobromide
Description: iNOS inhibitor, acts at arginine binding site
Biological Activity for S-Isopropylisothiourea hydrobromide
S-Isopropylisothiourea hydrobromide is a potent inhibitor of NO synthase, with selectivity for the inducible form.
Technical Data for S-Isopropylisothiourea hydrobromide
| M. Wt | 199.11 |
| Formula | C4H10N2S.HBr |
| Storage | Store at RT |
| CAS Number | 4269-97-0 |
| PubChem ID | 9813062 |
| InChI Key | SLGVZEOMLCTKRK-UHFFFAOYSA-N |
| Smiles | Br.CC(C)SC(=N)N |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for S-Isopropylisothiourea hydrobromide
References for S-Isopropylisothiourea hydrobromide
References are publications that support the biological activity of the product.
Garvey et al (1994) Potent and selective inhibition of human nitric oxide synthases. J.Biol.Chem. 269 26669 PMID: 7523409
Moore and Handy (1997) Selective inhibitors of neuronal nitric oxide synthase - is no NOS really good NOS for the nervous system? TiPS 18 204 PMID: 9226999
Handy et al (1995) Effect of S-methylisothiourea on neuronal nitric oxide synthase, nociception and blood pressure in the mouse. Br.J.Pharmacol. 115 68P
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Keywords: S-Isopropylisothiourea hydrobromide, S-Isopropylisothiourea hydrobromide supplier, iNOS, inhibitors, inhibits, arginine, binding, site, Nitric, Oxide, Signaling, Signalling, Inducible, NO, Synthases, 0897, Tocris Bioscience
Citations for S-Isopropylisothiourea hydrobromide
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Currently there are no citations for S-Isopropylisothiourea hydrobromide.
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