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StRIP16

Cat. No. 6575 Submit a Review Datasheet / COA / SDS

Discontinued Product

6575 has been discontinued.

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Description: Rab8a GTPase-binding stapled peptide
Datasheet
Citations
Reviews
Biological Activity Technical Data Datasheets References

Biological Activity for StRIP16

StRIP16 is a rab8a GTPase-binding stapled peptide (Kd = 12.7 μM). Cell permeable; localizes to the endomembrane system.

Technical Data for StRIP16

M. Wt 2300.61
Formula C116H154N24O26
Sequence DNEXQWFXYHLXFFNXV

(Modifications: Asp-1 = N-terminal Ac, X = (S)-2-(4-pentenyl)alanine, X-4 and X-8 stapled together with a double bond, X-12 and X-16 stapled together with a double bond, Val-17 = C-terminal amide)
Storage Store at -20°C
Smiles CC(C[C@@H](C(N[C@]1(CCC/C=C/CCC[C@](NC([C@@H](NC([C@@H](NC([C@@H](NC1=O)CC2=CC=CC=C2)=O)CC3=CC=CC=C3)=O)CC(N)=O)=O)(C(N[C@H](C(N)=O)C(C)C)=O)C)C)=O)NC([C@@H](NC([C@@H](NC([C@@]4(CCC/C=C/CCC[C@](NC([C@@H](NC([C@@H](NC([C@H](CC(O)=O)NC(C)=O)=O)CC(N)=O)=O)CCC(O)=O)=O)(C(N[C@H](C(N[C@H](C(N[C@H](C(N4)=O)CC5=CC=CC=C5)=O)CC6=CNC7=CC=CC=C67)=O)CCC(N)=O)=O)C)C)=O)CC8=CC=C(C=C8)O)=O)CC9=CN=CN9)=O)C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

References for StRIP16

References are publications that support the biological activity of the product.

Cromm et al (2016) Protease-resistant and cell-permeable double-stapled peptides targeting the Rab8a GTPase. ACS Chem.Biol. 11 2375 PMID: 27336832

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Keywords: StRIP16, StRIP16 supplier, RAb8a, binding, stapled, peptides, GTPase, binds, cell-permeable, Other, Small, Monomeric, GTPases, Stapled, Peptides, 6575, Tocris Bioscience

Citations for StRIP16

Citations are publications that use Tocris products.

Currently there are no citations for StRIP16.

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