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Submit ReviewTC-G 1003
Description: High affinity somatostatin sst2 agonist
Chemical Name: 3-[4-(3-Aminopropoxy)-7-chloro-3-(3,5-dimethylphenyl)-6-quinolinyl]phenol
Purity: ≥98% (HPLC)
Biological Activity for TC-G 1003
TC-G 1003 is a high affinity somatostatin sst2 receptor agonist (Ki = 0.025 nM). Inhibits growth hormone secretion and attenuates laser-induced ocular neovascular lesion size in rats.
Technical Data for TC-G 1003
| M. Wt | 432.94 |
| Formula | C26H25ClN2O2 |
| Storage | Store at -20°C |
| Purity | ≥98% (HPLC) |
| CAS Number | 1021912-42-4 |
| PubChem ID | 52936725 |
| InChI Key | GXGVWEMSSIKHOZ-UHFFFAOYSA-N |
| Smiles | CC1=CC(C3=C(OCCCN)C2=CC(C4=CC=CC(O)=C4)=C(Cl)C=C2N=C3)=CC(C)=C1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for TC-G 1003
References for TC-G 1003
References are publications that support the biological activity of the product.
Wolkenberg et al (2011) Design, synthesis, and evaluation of novel 3,6-diaryl-4-aminoalkoxyquinolines as selective agonists of somatostatin receptor subtype 2. J.Med.Chem. 54 2351 PMID: 21395312
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Keywords: TC-G 1003, TC-G 1003 supplier, TC-G1003, high, affinity, somatostatin, sst2, receptors, agonists, Somatostatin, Receptors, 5080, Tocris Bioscience
Citations for TC-G 1003
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