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TC HSD 21

Cat. No. 4575 Submit a Review Datasheet / COA / SDS

Discontinued Product

4575 has been discontinued.

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Description: Potent and selective 17β-hydroxysteroid dehydrogenase type 3 inhibitor
Chemical Name: 5-[(3-Bromo-4-hydroxyphenyl)methylene]-3-(4-methoxyphenyl)-2-thioxo-4-thiazolidinone
Purity: ≥99% (HPLC)
Datasheet
Citations
Reviews
Literature (2)
Biological Activity Technical Data Datasheets References

Biological Activity for TC HSD 21

TC HSD 21 is a potent 17β-hydroxysteroid dehydrogenase type 3 (17β-HSD3) inhibitor (IC50 values are 6 and 40 nM at human and mouse 17β-HSD3 respectively). Displays no activity at 17β-HSD1, 17β-HSD2, ERα, androgen receptors or glucocorticoid receptors.

Technical Data for TC HSD 21

M. Wt 422.32
Formula C17H12BrNO3S2
Storage Store at +4°C
Purity ≥99% (HPLC)
CAS Number 330203-01-5
PubChem ID 1774851
InChI Key HEFKAUYVLSGPGC-DHDCSXOGSA-N
Smiles S=C(S/C(C3=O)=C\C2=CC=C(O)C(Br)=C2)N3C1=CC=C(OC)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

References for TC HSD 21

References are publications that support the biological activity of the product.

Harada et al (2012) Identification of oxazolidinediones and thiazolidinediones as potent 17β-hydroxysteroid dehydrogenase type 3 inhibitors. Bioorg.Med.Chem.Lett. 22 504 PMID: 22137341

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Keywords: TC HSD 21, TC HSD 21 supplier, TCHSD21, 17beta, HSD3, 17b, 17β, hydroxysteroid, type, 3, potent, selective, inhibitors, inhibits, Other, Dehydrogenases, 4575, Tocris Bioscience

Citations for TC HSD 21

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