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Description: Inducer of neuronal differentiation in MSCs
Chemical Name: 1,2-Dihydro-N-hydroxy-2-oxo-3-(3-phenylpropyl)-6-quinoxalinecarboxamide
Biological Activity for TCS 2210
TCS 2210 is an inducer of neuronal differentiation in mesenchymal stem cells (MSCs) with specific phenotype change. Increases expression of neuronal markers β-III tubulin and NSE without cytotoxicity.
Compound Libraries for TCS 2210
TCS 2210 is also offered as part of the Tocriscreen Stem Cell Library. Find out more about compound libraries available from Tocris.
Technical Data for TCS 2210
| M. Wt | 323.35 |
| Formula | C18H17N3O3 |
| Storage | Store at -20°C |
| CAS Number | 1201916-31-5 |
| PubChem ID | 44607172 |
| InChI Key | ZOFZKGFBKISZRI-UHFFFAOYSA-N |
| Smiles | O=C(NO)C3=CC1=C(C=C3)NC(C(CCCC2=CC=CC=C2)=N1)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for TCS 2210
References for TCS 2210
References are publications that support the biological activity of the product.
Kim et al (2009) Discovery of a new and efficient small molecule for neuronal differentiation from mesenchymal stem cell. J.Med.Chem. 52 7931 PMID: 20014867
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Keywords: TCS 2210, TCS 2210 supplier, TCS2210, neuronal, inducers, differentiation, mesenchymal, stem, cells, MSC, induces, Mesenchymal, Stem, Cells, Neural, 3877, Tocris Bioscience
2 Citations for TCS 2210
Citations are publications that use Tocris products. Selected citations for TCS 2210 include:
Moshfegh et al (2016) A gonogenic stimulated transition of mouse embryonic stem cells with enhanced control of diverse differentiation pathways. PLoS One 6 25104 PMID: 27157261
Utta et al (2015) Orbital Fibroblasts From Graves' Orbitopathy Patients Share Functional and Immunophenotypic Properties With Mesenchymal Stem/Stromal Cells. Invest Ophthalmol Vis Sci 56 6549-57 PMID: 26457540
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
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Stem Cells Poster
Written by Rebecca Quelch and Stefan Przyborski from Durham University (UK), this poster describes the isolation of pluripotent stem cells, their maintenance in culture, differentiation, and the generation and potential uses of organoids.