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Submit ReviewTin protoporphyrin IX dichloride
Description: Heme oxygenase inhibitor
Biological Activity for Tin protoporphyrin IX dichloride
Tin protoporphyrin IX dichloride is a potent inhibitor of heme oxygenase. Prevents hyperbilirubinemia in neonates.
Technical Data for Tin protoporphyrin IX dichloride
| M. Wt | 750.25 |
| Formula | C34H32Cl2N4O4Sn |
| Storage | Store at RT |
| CAS Number | 14325-05-4 |
| PubChem ID | 3000478 |
| InChI Key | ZUQBMBXSEXXKTO-UHFFFAOYSA-L |
| Smiles | C=CC1=C(/C=C3\N=C(/C=C(N5[Sn](Cl)6Cl)/C(C)=C(CCC(O)=O)/C5=C4)C(C=C)=C3C)N6C(/C=C2/C(C)=C(CCC(O)=O)C/4=N2)=C1C |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Tin protoporphyrin IX dichloride
References for Tin protoporphyrin IX dichloride
References are publications that support the biological activity of the product.
Drummond and Kappas (1981) Prevention of neonatal hyperbilirubinemia by tin protoporphyrin IX, a potent competitive inhibitor of haem oxidation. Proc.Natl.Acad.Sci.U.S.A. 78 6466 PMID: 6947237
Grundemar and Ny (1997) Pitfalls using metalloporphyrins in carbon monoxide research. TiPS 18 193 PMID: 9226997
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Keywords: Tin protoporphyrin IX dichloride, Tin protoporphyrin IX dichloride supplier, Heme, haem, oxygenase, inhibitors, inhibits, Oxygenases, Oxidases, Tin, protoporphyrinIX, dichloride, Oxygenase, 0747, Tocris Bioscience
3 Citations for Tin protoporphyrin IX dichloride
Citations are publications that use Tocris products. Selected citations for Tin protoporphyrin IX dichloride include:
Guimarães et al (2012) Mitochondrial uncouplers inhibit hepatic stellate cell activation. BMC Gastroenterol 12 68 PMID: 22686625
Duann et al (2019) Data on characterization of metalloporphyrin-mediated HO-1 and DAF induction in rat glomeruli and podocytes. Data Brief 22 279 PMID: 30591946
Ye et al (2013) Astaxanthin protects against MPP(+)-induced oxidative stress in PC12 cells via the HO-1/NOX2 axis. BMC Neurosci 13 156 PMID: 23272707
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