Tocriscreen Epigenetics 3.0

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Description: A library of 160 epigenetic compounds (100 μL, 10 mM DMSO solutions) for high throughput screening, high content screening, target validation and assay development
Datasheet
Citations (2)
Reviews
Literature (1)

Biological Activity for Tocriscreen Epigenetics 3.0

Tocriscreen Epigenetics Library is a library of 160 epigenetic compounds (100 μL, 10 mM solutions). Contains compounds covering >40 epigenetic targets including epigenetic readers, writers, erasers and transcriptional modulators. Includes the latest chemical tools to target p300/CBP, PCAF, BRPF1 and SMYD2.

This library replaces the Tocriscreen Epigenetics Library (Cat. No. 6801).

If this library does not suit your needs, please submit your requirements through our Tocriscreen PRO custom compound library service.

Key Format and Product Details for Tocriscreen Epigenetics 3.0

  • 96-well racks with Matrix storage tubes & SepraSeal caps
  • Pre-dissolved in DMSO
  • Exceptional purity
  • Many compounds are exclusive to Tocris
  • Full chemical and biological data available
  • Proven solubility, biological activity and stability in DMSO
Target Classes Covered by the Tocriscreen Epigenetics Library

The Tocriscreen Epigenetics Compound Library contains bioactive compounds covering a diverse range of molecular targets within the following categories: epigenetic writers (43%), transcription modulators (23%), epigenetic erasers (19%), and epigenetic readers (16%).

Request Compound List

To request a list of the compounds available in the Tocriscreen Epigenetics 3.0 please click the request tile below. Compound lists can be provided in Excel or SD format.

Request compound list for Tocriscreen Epigenetics 3.0

Technical Data for Tocriscreen Epigenetics 3.0

Storage Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for Tocriscreen Epigenetics 3.0

Certificate of Analysis is currently unavailable on-line.
Please contact Customer Service

References for Tocriscreen Epigenetics 3.0

References are publications that support the biological activity of the product.

If you know of a relevant reference for Tocriscreen Epigenetics 3.0, please let us know.

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2 Citations for Tocriscreen Epigenetics 3.0

Citations are publications that use Tocris products. Selected citations for Tocriscreen Epigenetics 3.0 include:

Andricovich et al (2018) Loss of KDM6A activates super-enhancers to induce gender-specific squamous-like pancreatic cancer and confers sensitivity to BET inhibitors. Cancer Cell 33 512 PMID: 29533787

Zhang et al (2023) Deciphering a global source of non-genetic heterogeneity in cancer cells. Nucleic Acids Res. 51 9019 PMID: 37587722


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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


Tocriscreen Compound Libraries

Tocriscreen Compound Libraries

This brochure gives an overview of the unique TocriscreenTM bioactive compound library range, including

  • Tocriscreen 2.0 Compound Library
  • Focused Tocriscreen Libraries
  • Tocriscreen FDA-approved Drug Library
  • Tocriscreen PRO Custom Service