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Submit ReviewW-9 hydrochloride is a calmodulin antagonist (inhibits calmodulin-activated PDE activity with an IC50 of 72 μM).
M. Wt | 377.33 |
Formula | C16H21ClN2O2S.HCl |
Storage | Store at RT |
CAS Number | 69762-85-2 |
PubChem ID | 2735339 |
InChI Key | FGWDLQXTCSKXSK-UHFFFAOYSA-N |
Smiles | Cl.NCCCCCCNS(=O)(=O)C1=CC=C2C(Cl)=CC=CC2=C1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Hidaka et al (1979) Selective inhibitors of Ca2+-binding modulator of phosphodiesterase produce vascular relaxation and inhibit actin-myosin interaction. Mol.Pharmacol. 15 49 PMID: 218093
Hidaka et al (1981) N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide, a calmodulin antagonist, inhibits cell proliferation. Proc.Natl.Acad.Sci.U.S.A. 78 4354 PMID: 6945588
Keywords: W-9 hydrochloride, W-9 hydrochloride supplier, Calmodulin, antagonists, Ca2+, Binding, Protein, modulators, Calcium, Signaling, Signalling, Ca2+-calmodulin-dependent, phosphodiesterase, 0370, Tocris Bioscience
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