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Discontinued Product
TB4855-RMU has been discontinued.
View all Ancillary Material Grade Small Molecules products.
Description: WIKI4 synthesized to Ancillary Material Grade
Chemical Name: 2-[3-[[4-(4-Methoxyphenyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]propyl]-1H-benz[de]isoquinoline-1,3(2H)-dione
Purity: ≥98% (HPLC)
Biological Activity for WIKI4
WIKI4 is an ancillary Material Grade version of product WIKI4 (Cat. No. 4855). Suitable for use as an ancillary reagent in the further manufacturing of cell therapies.
Find out more about our Ancillary Material Grade product range.
Technical Data for WIKI4
| M. Wt | 521.59 |
| Formula | C29H23N5O3S |
| Storage | Store at -20°C(±5°C) |
| Purity | ≥98% (HPLC) |
| CAS Number | 838818-26-1 |
| InChI Key | RNUXIZKXJOGYQP-UHFFFAOYSA-N |
| Smiles | O=C(C1=C2C(C3=O)=CC=CC2=CC=C1)N3CCCSC4=NN=C(C5=CC=NC=C5)N4C6=CC=C(OC)C=C6 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for WIKI4
Certificate of Analysis is currently unavailable on-line.
Please contact Customer Service
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References for WIKI4
References are publications that support the biological activity of the product.
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Keywords: WIKI4, WIKI4 supplier, Ancillary, Material, Grade, Wnt, signaling, signalling, inhibitors, inhibits, b-catenin, beta-catenin, β-catenin, tankyrase, TNKS2, manufacturing, gene, cell, therapies, therapy, GMP, Small, Molecules, TB4855-RMU, Tocris Bioscience
Citations for WIKI4
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Currently there are no citations for WIKI4.
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Stem Cell Research Product Guide
This product guide provides a background to the use of small molecules in stem cell research and lists over 200 products for use in:
- Self-renewal and Maintenance
- Differentiation
- Reprogramming
- Organoid Generation
- GMP and Ancillary Material Grade Products
Stem Cells Scientific Review
Written by Kirsty E. Clarke, Victoria B. Christie, Andy Whiting and Stefan A. Przyborski, this review provides an overview of the use of small molecules in the control of stem cell growth and differentiation. Key signaling pathways are highlighted, and the regulation of ES cell self-renewal and somatic cell reprogramming is discussed. Compounds available from Tocris are listed.
Stem Cell Workflow Poster
Stem cells have potential as a source of cells and tissues for research and treatment of disease. This poster summarizes some key protocols demonstrating the use of small molecules across the stem cell workflow, from reprogramming, through self-renewal, storage and differentiation to verification. Advantages of using small molecules are also highlighted.
Stem Cells Poster
Written by Rebecca Quelch and Stefan Przyborski from Durham University (UK), this poster describes the isolation of pluripotent stem cells, their maintenance in culture, differentiation, and the generation and potential uses of organoids.