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Description: TRPM8 agonist; cooling agent
Chemical Name: N-Ethyl-5-methyl-2-(1-methylethyl)cyclohexanecarboxamide
Purity: ≥99% (HPLC)
Biological Activity for WS 3
WS 3 is a cooling agent that is an agonist at TRPM8 receptors (EC50 = 3.7 μM).
Technical Data for WS 3
| M. Wt | 211.34 |
| Formula | C13H25NO |
| Storage | Store at RT |
| Purity | ≥99% (HPLC) |
| CAS Number | 39711-79-0 |
| PubChem ID | 62907 |
| InChI Key | VUNOFAIHSALQQH-UHFFFAOYSA-N |
| Smiles | CC1CC(C(NCC)=O)C(C(C)C)CC1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for WS 3
References for WS 3
References are publications that support the biological activity of the product.
Behrendt et al (2004) Characterization of the mouse cold-menthol receptor TRPM8 and vanilloid receptor type-1 VR1 using a fluorometric imaging plate reader (FLIPR) assay. Br.J.Pharmacol. 141 737 PMID: 14757700
Bodding (2007) TRP proteins and cancer. Cell Signal. 19 617 PMID: 17029734
Rovner (2007) Better than mint. C&EN 85 95
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Keywords: WS 3, WS 3 supplier, TRPM8, agonists, cooling, agent, Channels, Transient, Receptor, Potential, WS3, TRPM, 2927, Tocris Bioscience
Citations for WS 3
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Currently there are no citations for WS 3.
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