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Submit ReviewNon-benzodiazepine agent that acts as an agonist at the benzodiazepine site. Displays hypnotic, anxiolytic, myorelaxant and anticonvulsant activity.
M. Wt | 305.33 |
Formula | C17H15N5O |
Storage | Desiccate at +4°C |
Purity | ≥99% (HPLC) |
CAS Number | 151319-34-5 |
PubChem ID | 5719 |
InChI Key | HUNXMJYCHXQEGX-UHFFFAOYSA-N |
Smiles | CC(N(CC)C1=CC=CC(C3=CC=NC2=C(C#N)C=NN23)=C1)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Gaudreault et al (1995) Pharmacokinetics and anticonvulsant effect of a new hypnotic, CL 284,846, in rats. Pharm.Res. 12 1592 PMID: 8592655
Sanger et al (1996) Comparison of the pharmacological profiles of the hypnotic drugs, zal. and zol. Eur.J.Pharmacol. 313 35 PMID: 8905326
Keywords: Zaleplon, Zaleplon supplier, Benzodiazepine, agonists, GABAA, Receptors, CL284846, CL, 284846, 3655, Tocris Bioscience
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Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
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Written by Ian Martin, Norman Bowery and Susan Dunn, this review provides a history of the GABA receptor, as well as discussing the structure and function of the various subtypes and the clinical potential of receptor modulators; compounds available from Tocris are listed.
The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.