Applications for Epigenetic Chemical Probes in Non-Oncology Research
Epigenetic chemical probes are well established tools in oncology research but their application to other...
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Welcome to the Tocris blog! If you’re looking for fresh insights into new tools for life science research, or are interested in the latest news and events from Tocris then you’re in the right place. Read on to discover our latest content.
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Using Chemical Probes – A Brief Guide
With such a high level of discussion around the reproducibility of experiments described in the peer-reviewed literature, it is becoming increasingly prudent to scrutinize the tools that we use to conduct our research. Selecting a “good” probe is key to generating reliable and...
Read moreDeveloping Chemical Probes for Epigenetic Targets
The Structural Genomics Consortium (SGC) was set-up in 2004, with the goal of solving the protein structures of relevance to human disease. Since then the mission has expanded to advancing drug discovery via open access...
Read moreTargeting the Immune System in Cancer with Small Molecules
Recent clinical successes in targeting the immune system for the treatment of cancer have harnessed biologicals, including antibodies, proteins, engineered cells and oncolytic viruses. Small molecules directed at the immune system offer advantages over...
Read moreFive Reasons to use Small Molecules in Stem Cell Research
Stem cells are defined by their ability to differentiate into specialized cells and to self-renew. Pluripotent stem cells (PSCs), of which embryonic stem cells (ESCs)...
Read moreSmall Molecules for Neural Induction of Stem Cells
Differentiation of human induced pluripotent stem cells (hiPSCs) into functional neurons is an exciting area of research, with considerable therapeutic potential...
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