1-Deazaadenosine

Cat. No. 4488 2 篇引用文献提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

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说明： Adenosine deaminase inhibitor

化学名： 3-β-D-Ribofuranosyl-3H-imidazo[4,5-b]pyridin-7-amine

纯度： ≥98% (HPLC)

引用文献 (2)

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for 1-Deazaadenosine

1-Deazaadenosine is an inhibitor of adenosine deaminase (K_i = 0.66 μM). Demonstrates antitumor activity in a range of leukemia cell lines.

技术数据 for 1-Deazaadenosine

分子量	266.25
公式	C₁₁H₁₄N₄O₄
储存	Store at +4°C
纯度	≥98% (HPLC)
CAS Number	14432-09-8
PubChem ID	159738
InChI Key	NVUDDRWKCUAERS-PNHWDRBUSA-N
Smiles	NC1=C2C(N([C@H]3[C@H](O)[C@H](O)[C@@H](CO)O3)C=N2)=NC=C1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for 1-Deazaadenosine

	溶剂	最高浓度 mg/mL	最高浓度 mM
溶解性
溶解性	DMSO	6.66	25

制备储备液 for 1-Deazaadenosine

以下数据基于产品分子量 266.25。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

浓度/溶剂体积/质量	1 mg	5 mg	10 mg
0.25 mM	15.02 mL	75.12 mL	150.23 mL
1.25 mM	3 mL	15.02 mL	30.05 mL
2.5 mM	1.5 mL	7.51 mL	15.02 mL
12.5 mM	0.3 mL	1.5 mL	3 mL

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产品说明书 for 1-Deazaadenosine

分析证书/产品说明书

化学品安全技术说明书

参考文献 for 1-Deazaadenosine

参考文献是支持产品生物活性的出版物。

Cristalli et al (1993) Adenosine deaminase inhibitors: Structure-activity relationships in 1-deazaadenosine and erythro-9-(2-hydroxy-3-nonyl)adenine analogues. Drug Dev.Res. 28 253

Cristalli et al (1987) Improved synthesis and antitumor activity of 1-deazaadenosine. J.Med.Chem. 30 1686 PMID: 3625714

If you know of a relevant reference for 1-Deazaadenosine, please let us know.