Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit Review16,16-Dimethyl Prostaglandin E2
说明： Synthetic prostaglandin E2 (Cat. No. 2296) derivative; regulates HSC development
化学名： (5Z,11α,13E,15R)-11,15-Dihydroxy-16,16-dimethyl-9-oxo-prosta-5,13-dien-1oic acid
纯度： ≥95% (HPLC)
生物活性 for 16,16-Dimethyl Prostaglandin E2
16,16-Dimethyl Prostaglandin E2 is a synthetic derivative of prostaglandin E2 (Cat. No. 2296). Increases embryonic stem cell (ESC) hematopoietic colony formation in mouse bone marrow. Also induces an increase in hematopoietic stem cell (HSC) numbers and enhances Wnt activity within the HSC population in zebrafish embryos.
技术数据 for 16,16-Dimethyl Prostaglandin E2
| 分子量 | 380.52 |
| 公式 | C22H36O5 |
| 储存 | Store at -80°C |
| 纯度 | ≥95% (HPLC) |
| CAS Number | 39746-25-3 |
| PubChem ID | 5283066 |
| InChI Key | QAOBBBBDJSWHMU-WMBBNPMCSA-N |
| Smiles | O=C1[C@H](C/C=C\CCCC(O)=O)[C@@H](/C=C/[C@@H](O)C(C)(C)CCCC)[C@H](O)C1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
溶解性数据 for 16,16-Dimethyl Prostaglandin E2
| 溶解性 | Soluble in methyl acetate (supplied pre-dissolved -10mg/ml) |
产品说明书 for 16,16-Dimethyl Prostaglandin E2
参考文献 for 16,16-Dimethyl Prostaglandin E2
参考文献是支持产品生物活性的出版物。
Lord et al (2007) Prostaglandin E2: making more of your marrow. Cell Cycle. 6 3054 PMID: 18075310
Goessling et al (2009) Genetic interaction of PGE2 and wnt signaling regulates developmental specification of stem cells and regeneration. Cell. 136 1136 PMID: 19303855
North et al (2007) Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis. Nature. 447 1007 PMID: 17581586
Heffner et al (2018) Prostaglandin E2 increases lentiviral vector transduction efficiency of adult human hematopoietic stem and progenitor cells. Mol.Ther. 26 320 PMID: 29102562
If you know of a relevant reference for 16,16-Dimethyl Prostaglandin E2, please let us know.
按标靶查看相关产品
按产品操作查看相关产品
关键词: 16,16-Dimethyl Prostaglandin E2, 16,16-Dimethyl Prostaglandin E2 supplier, synthetic, prostaglandin, prostanoid, receptors, agonists, hematopoietic, haematopoietic, stem, cells, HSCs, PGE2, organoids, HSC, Prostanoid, Receptors, Stem, Cell, Signaling, Proliferation, Viral, Transduction, Enhancers, Hematopoietic, Cells, 4027, Tocris Bioscience
3 篇 16,16-Dimethyl Prostaglandin E2 的引用文献
引用文献是使用了 Tocris 产品的出版物。 16,16-Dimethyl Prostaglandin E2 的部分引用包括：
Jansen et al (2015) Prostaglandin E2 promotes MYCN non-amplified neuroblastoma cell survival via β-catenin stabilization. Oncotarget 19 210 PMID: 25266063
Yoko et al (2021) COX2 regulates senescence secretome composition and senescence surveillance through PGE2. Cell Rep 34 108860 PMID: 33730589
Helen M et al (2017) Prostaglandin E2 is essential for efficacious skeletal muscle stem-cell function, augmenting regeneration and strength. Proc Natl Acad Sci U S A 114 6675-6684 PMID: 28607093
您是否知道使用了 Tocris 16,16-Dimethyl Prostaglandin E2 的优秀论文？ 请告知我们.
16,16-Dimethyl Prostaglandin E2 的评论
目前没有该产品的评论。 Be the first to review 16,16-Dimethyl Prostaglandin E2 and earn rewards!
Have you used 16,16-Dimethyl Prostaglandin E2?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image