2-Chloroadenosine

Cat. No. 3136 1 次引用提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Pricing	Availability		Qty

说明： Adenosine receptor agonist

别名： 2-CADO

化学名： 6-Amino-2-chloropurine riboside

纯度： ≥98% (HPLC)

引用文献 (1)

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for 2-Chloroadenosine

2-Chloroadenosine is a metabolically stable analog of adenosine that behaves as an adenosine receptor agonist (K_i values are 300, 80 and 1900 nM for A₁, A_2A and A₃ receptors respectively). Anticonvulsive in vivo.

化合物库 for 2-Chloroadenosine

2-Chloroadenosine is also offered as part of the Tocriscreen 2.0 Max. 了解 Tocris 化合物库的更多信息。

技术数据 for 2-Chloroadenosine

分子量	301.69
公式	C₁₀H₁₂ClN₅O₄
储存	Store at +4°C
纯度	≥98% (HPLC)
CAS Number	146-77-0
PubChem ID	8974
InChI Key	BIXYYZIIJIXVFW-UUOKFMHZSA-N
Smiles	O[C@@H]1[C@@H](CO)O[C@@H](N3C2=NC(Cl)=NC(N)=C2N=C3)[C@@H]1O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for 2-Chloroadenosine

	溶剂	最高浓度 mg/mL	最高浓度 mM
溶解性
	water	7.54	25
	DMSO	30.17	100

制备储备液 for 2-Chloroadenosine

以下数据基于产品分子量 301.69。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

浓度/溶剂体积/质量	1 mg	5 mg	10 mg
1 mM	3.31 mL	16.57 mL	33.15 mL
5 mM	0.66 mL	3.31 mL	6.63 mL
10 mM	0.33 mL	1.66 mL	3.31 mL
50 mM	0.07 mL	0.33 mL	0.66 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

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产品说明书 for 2-Chloroadenosine

分析证书/产品说明书

化学品安全技术说明书

参考文献 for 2-Chloroadenosine

参考文献是支持产品生物活性的出版物。

Mathot et al (1996) Pharmacokinetic-haemodynamic relationships of 2-chloroadenosine at adenosine A₁ and A_2a receptors in vivo. Br.J.Pharmacol. 118 369 PMID: 8735640

Pourgholami et al (1997) Intra-amygdala infusion of 2-chloroadenosine suppresses amygdala-kindled seizures. Brain Res. 775 37 PMID: 9439826

Abdul-Ghani et al (1997) The protective effect of 2-chloroadenosine against the development of amygdala kindling and on amygdala-kindled seizures. Eur.J.Pharmacol. 326 7 PMID: 9178649

If you know of a relevant reference for 2-Chloroadenosine, please let us know.

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关键词: 2-Chloroadenosine, 2-Chloroadenosine supplier, adenosines, receptors, agonists, Non-Selective, 2CADO, 2-CADO, Non-selective, Adenosine, 3136, Tocris Bioscience

1 篇 2-Chloroadenosine 的引用文献

引用文献是使用了 Tocris 产品的出版物。 2-Chloroadenosine 的部分引用包括：

Nowak et al (2010) The A2aR adenosine receptor controls cytokine production in iNKT cells. Front Cell Neurosci 40 682 PMID: 20039304

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