2-Methyl-5-hydroxytryptamine hydrochloride

Name: 2-Methyl-5-hydroxytryptamine hydrochloride
Brand: Tocris Bioscience
SKU: 0558

Cat. No. 0558 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

0558 has been discontinued.

View all 5-HT<sub>3</sub> Receptors products.

说明： 5-HT₃ agonist/potent 5-HT₆ ligand

纯度： ≥98% (HPLC)

说明书

引用文献

文献 (1)

生物活性技术数据说明书参考文献

生物活性

5-HT₃ agonist (K_i = 1200 nM) and potent 5-HT₆ ligand (K_i = 46 nM).

技术数据

分子量	226.71
公式	C₁₁H₁₄N₂O.HCl
储存	Store at RT
纯度	≥98% (HPLC)
CAS Number	845861-49-6
PubChem ID	11492320
InChI Key	ZNVRHQPXSBWLQP-UHFFFAOYSA-N
Smiles	Cl.CC1=C(CCN)C2=CC(O)=CC=C2N1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书

分析证书/产品说明书

化学品安全技术说明书

参考文献

参考文献是支持产品生物活性的出版物。

Craig et al (1990) 5-Methoxytryptamine and 2-methyl-5-hydroxytryptamine-induced desensitization as a discriminative tool for the 5-HT₃ and putative 5-HT₄ receptors in guinea pig ileum. Naunyn Schmiedebergs Arch.Pharmacol. 342 9 PMID: 2402303

Glennon et al (2000) 2-substituted tryptamines: agents with selectivity for 5-HT₆ serotonin receptors. J.Med.Chem. 43 1011 PMID: 10715164

Ismaiel et al (1990) 5-HT₁ and 5-HT₂ binding profiles of the serotonergic agents α-methyl serotonin and 2-methylserotonin. J.Med.Chem. 33 755 PMID: 2299641

Wilson et al (1990) 5-Hydroxytryptamine₃ receptors mediate tachycardia in conscious instrumented dogs. J.Pharmacol.Exp.Ther. 252 683 PMID: 1968974

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