2-Palmitoylglycerol

Discontinued Product

2206 has been discontinued.

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说明: Endogenous lipid; enhances activity of 2-arachidonylglycerol (Cat. No. 1298)
别名: 2-Palm-Gl,2-PG
化学名: 2-Hydroxy-1-(hydroxymethyl)ethyl hexadecanoic acid ester
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引用文献
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生物活性 for 2-Palmitoylglycerol

2-Palmitoylglycerol is a endogenous fatty acid glycerol ester that enhances activity of 2-arachidonylglycerol (Cat. No. 1298). Does not bind to CB1 or CB2 cannabinoid receptors, but potentiates the apparent binding of 2-AG and increases its ability to inhibit adenylyl cyclase. Enhances in vivo cannabinoid effects of 2-AG following combined administration with 2-linoleoylglycerol.

技术数据 for 2-Palmitoylglycerol

分子量 330.51
公式 C19H38O4
储存 Store at -20°C
CAS Number 23470-00-0
PubChem ID 123409
InChI Key BBNYCLAREVXOSG-UHFFFAOYSA-N
Smiles OCC(CO)OC(CCCCCCCCCCCCCCC)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for 2-Palmitoylglycerol

参考文献 for 2-Palmitoylglycerol

参考文献是支持产品生物活性的出版物。

Ben-Shabat et al (1998) An entourage effect: inactive endogenous fatty acid glycerol esters enhance 2-arachidonyl-glycerol cannabinoid activity. Eur.J.Pharmacol. 353 23 PMID: 9721036

Gallily et al (2000) 2-Arachidonylglycerol, an endogenous cannabinoid, inhibits tumor necrosis factor-α production in murine macrophages, and in mice. Eur.J.Pharmacol. 406 R5 PMID: 11011050

Walker et al (2002) Endocannabinoids and related fatty acid derivatives in pain modulation. Chem.Phys.Lipids 121 159 PMID: 12505698

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关键词: 2-Palmitoylglycerol, 2-Palmitoylglycerol supplier, Endogenous, lipid, enhances, activity, 2-AG, cannabinoid, receptors, fatty, acid, glycerol, ester, 2-arachidonylglycerol, 2-Palm-Gl, 2-PG, Other, Cannabinoids, 2206, Tocris Bioscience

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Cannabinoid Receptor Ligands Scientific Review

Cannabinoid Receptor Ligands Scientific Review

Written by Roger Pertwee, this review discusses compounds which affect the activity of the endocannabinoid system, focusing particularly on ligands that are most widely used as experimental tools and denotes compounds available from Tocris.