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Submit Review2-Pyridylethylamine dihydrochloride is a histamine H1 receptor agonist that produces vasoconstriction in vivo.
2-Pyridylethylamine dihydrochloride is also offered as part of the Tocriscreen 2.0 Max. 了解 Tocris 化合物库的更多信息。
分子量 | 195.09 |
公式 | C7H10N2.2HCl |
储存 | Desiccate at RT |
纯度 | ≥99% (HPLC) |
CAS Number | 3343-39-3 |
PubChem ID | 201148 |
InChI Key | GPIFKSYYILNJNR-UHFFFAOYSA-N |
Smiles | Cl.Cl.NCCC1=NC=CC=C1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
溶剂 | 最高浓度 mg/mL | 最高浓度 mM | |
---|---|---|---|
溶解性 | |||
water | 19.51 | 100 | |
DMSO | 9.75 | 50 |
以下数据基于产品分子量 195.09。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
浓度/溶剂体积/质量 | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 5.13 mL | 25.63 mL | 51.26 mL |
5 mM | 1.03 mL | 5.13 mL | 10.25 mL |
10 mM | 0.51 mL | 2.56 mL | 5.13 mL |
50 mM | 0.1 mL | 0.51 mL | 1.03 mL |
参考文献是支持产品生物活性的出版物。
Martinez-Mir et al (1992) Effect of histamine and histamine analogues on human isolated myometrial strips. Br.J.Pharmacol. 107 528 PMID: 1358393
Arai and Chiba (1999) Endothelium-dependent vasodilation mechanisms by histamine in simian but not in canine femoral arterial branches. J.Auton.Pharmacol. 19 267 PMID: 10759332
If you know of a relevant reference for 2-Pyridylethylamine dihydrochloride, please let us know.
关键词: 2-Pyridylethylamine dihydrochloride, 2-Pyridylethylamine dihydrochloride supplier, H1, receptor, agonists, Receptors, Histamine, histaminergic, 2478, Tocris Bioscience
引用文献是使用了 Tocris 产品的出版物。 2-Pyridylethylamine dihydrochloride 的部分引用包括:
Jain et al (2018) Melanotan II causes hypothermia in mice by activation of mast cells and stimulation of histamine 1 receptors. Am J Physiol Endocrinol Metab 315 E357 PMID: 29812984
Ashina et al (2015) Histamine Induces Vascular Hyperpermeability by Increasing Blood Flow and Endothelial Barrier Disruption In Vivo. Mol Med Rep 10 e0132367 PMID: 26158531
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