2-Pyridylethylamine dihydrochloride

Pricing Availability   Qty
说明: H1 agonist
化学名: 2-Pyridineethanamine dihydrochloride
纯度: ≥99% (HPLC)
说明书
引用文献 (2)
评论
文献 (1)

生物活性 for 2-Pyridylethylamine dihydrochloride

2-Pyridylethylamine dihydrochloride is a histamine H1 receptor agonist that produces vasoconstriction in vivo.

化合物库 for 2-Pyridylethylamine dihydrochloride

2-Pyridylethylamine dihydrochloride is also offered as part of the Tocriscreen 2.0 Max. 了解 Tocris 化合物库的更多信息。

技术数据 for 2-Pyridylethylamine dihydrochloride

分子量 195.09
公式 C7H10N2.2HCl
储存 Desiccate at RT
纯度 ≥99% (HPLC)
CAS Number 3343-39-3
PubChem ID 201148
InChI Key GPIFKSYYILNJNR-UHFFFAOYSA-N
Smiles Cl.Cl.NCCC1=NC=CC=C1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for 2-Pyridylethylamine dihydrochloride

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
water 19.51 100
DMSO 9.75 50

制备储备液 for 2-Pyridylethylamine dihydrochloride

以下数据基于产品分子量 195.09。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 5.13 mL 25.63 mL 51.26 mL
5 mM 1.03 mL 5.13 mL 10.25 mL
10 mM 0.51 mL 2.56 mL 5.13 mL
50 mM 0.1 mL 0.51 mL 1.03 mL

Molarity Calculator

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Reconstitution Calculator

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Dilution Calculator

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产品说明书 for 2-Pyridylethylamine dihydrochloride

分析证书/产品说明书
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参考文献 for 2-Pyridylethylamine dihydrochloride

参考文献是支持产品生物活性的出版物。

Martinez-Mir et al (1992) Effect of histamine and histamine analogues on human isolated myometrial strips. Br.J.Pharmacol. 107 528 PMID: 1358393

Arai and Chiba (1999) Endothelium-dependent vasodilation mechanisms by histamine in simian but not in canine femoral arterial branches. J.Auton.Pharmacol. 19 267 PMID: 10759332


If you know of a relevant reference for 2-Pyridylethylamine dihydrochloride, please let us know.

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查看全部 Histamine H1 Receptor Agonists

关键词: 2-Pyridylethylamine dihydrochloride, 2-Pyridylethylamine dihydrochloride supplier, H1, receptor, agonists, Receptors, Histamine, histaminergic, 2478, Tocris Bioscience

2 篇 2-Pyridylethylamine dihydrochloride 的引用文献

引用文献是使用了 Tocris 产品的出版物。 2-Pyridylethylamine dihydrochloride 的部分引用包括:

Jain et al (2018) Melanotan II causes hypothermia in mice by activation of mast cells and stimulation of histamine 1 receptors. Am J Physiol Endocrinol Metab 315 E357 PMID: 29812984

Ashina et al (2015) Histamine Induces Vascular Hyperpermeability by Increasing Blood Flow and Endothelial Barrier Disruption In Vivo. Mol Med Rep 10 e0132367 PMID: 26158531


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该领域的文献

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*请注意,Tocris 仅会向正规科研企业/机构地址发送文献。


Histamine Receptors Scientific Review

Histamine Receptors Scientific Review

Written by Iwan de Esch and Rob Leurs, this review provides a synopsis of the different histamine receptor subtypes and the ligands that act upon them; compounds available from Tocris are listed.