2-ThioUTP tetrasodium salt

Cat. No. 3280 3 篇引用文献提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

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说明： Potent and selective P2Y₂ agonist

化学名： 2-Thiouridine 5'-triphosphate tetrasodium salt

纯度： ≥95% (HPLC)

引用文献 (3)

文献 (1)

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for 2-ThioUTP tetrasodium salt

2-ThioUTP tetrasodium salt is a potent and selective P2Y₂ agonist (EC₅₀ values are 0.035, 0.35 and 1.5 μM for hP2Y₂, hP2Y₄ and hP2Y₆ receptors respectively).

技术数据 for 2-ThioUTP tetrasodium salt

分子量	588.13
公式	C₉H₁₁N₂Na₄O₁₄P₃S
储存	Store at -20°C
纯度	≥95% (HPLC)
CAS Number	1343364-70-4
PubChem ID	54591573
InChI Key	QCBCNKBBEOQRRB-ODQFIEKDSA-J
Smiles	[Na+].[Na+].[Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O)N1C=CC(=O)NC1=S

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for 2-ThioUTP tetrasodium salt

溶解性	Soluble in water (supplied pre-dissolved at a concentration of 10mM)

产品说明书 for 2-ThioUTP tetrasodium salt

分析证书/产品说明书

化学品安全技术说明书

参考文献 for 2-ThioUTP tetrasodium salt

参考文献是支持产品生物活性的出版物。

El-Tayeb et al (2006) Synthesis and structure-activity relationships of uracil nucleotide derivatives and analogues as agonists at human P2Y₂, P2Y₄ and P2Y₆ receptors. J.Med.Chem. 49 7076 PMID: 17125260

Ko et al (2008) Synthesis and potency of novel uracil nucleotides and derivatives as P2Y₂ and P2Y₆ receptor agonists. Bioorg.Med.Chem. 16 6319 PMID: 18514530

If you know of a relevant reference for 2-ThioUTP tetrasodium salt, please let us know.

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关键词: 2-ThioUTP tetrasodium salt, 2-ThioUTP tetrasodium salt supplier, Potent, selective, P2Y2, agonists, Receptors, Purinergic, purinoceptors, P2Y, 3280, Tocris Bioscience

3 篇 2-ThioUTP tetrasodium salt 的引用文献

引用文献是使用了 Tocris 产品的出版物。 2-ThioUTP tetrasodium salt 的部分引用包括：

Martín-Gil et al (2012) Silencing of P2Y(2) receptors reduces intraocular pressure in New Zealand rabbits. Br J Pharmacol 165 1163 PMID: 21740413

Alkhani et al (2014) Contribution of TRPC3 to store-operated calcium entry and inflammatory transductions in primary nociceptors. Mol Brain 10 43 PMID: 24965271

Matsumoto et al (2011) Uridine adenosine tetraphosphate-induced contraction is increased in renal but not pulmonary arteries from DOCA-salt hypertensive rats. Am J Physiol Heart Circ Physiol 301 H409 PMID: 21551273

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