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(2R/S)-6-PNG

Cat. No. 6651 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

6651 has been discontinued.

View all Ca<sub>V</sub>3.x Channels (T-type) products.
说明： CaV3.2 blocker; active in vivo
化学名： 2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-6-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one
纯度： ≥98% (HPLC)
说明书
引用文献
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生物活性 技术数据 说明书 参考文献

生物活性 for (2R/S)-6-PNG

(2R/S)-6-PNG is a Cav3.2 (T-type) Ca2+ channel blocker (IC50 = 991 nM). Suppresses neuropathic allodynia in mouse pain models.

技术数据 for (2R/S)-6-PNG

分子量 340.37
公式 C20H20O5
储存 Store at -20°C
纯度 ≥98% (HPLC)
CAS Number 68682-01-9
PubChem ID 3519901
InChI Key YHWNASRGLKJRJJ-UHFFFAOYSA-N
Smiles C/C(C)=C\CC1=C(C=C2OC(C3=CC=C(C=C3)O)CC(C2=C1O)=O)O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for (2R/S)-6-PNG

参考文献是支持产品生物活性的出版物。

Sekiguchi et al (2018) Blockade of T-type calcium channels by 6-prenylnaringenin, a hop component, alleviates neuropathic and visceral pain in mice. Neuropharmacology 138 232 PMID: 29913186

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关键词: (2R/S)-6-PNG, (2R/S)-6-PNG supplier, T-type, calcium, channel, blockers, Cav3, pain, in, vivo, neuropathic, allodynia, Cav3.x, Channels, 6651, Tocris Bioscience

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