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Submit Review3-AQC
说明： 5-HT3 antagonist
化学名： 3-(4-Allylpiperazin-1-yl)-2-quinoxalinecarbonitrile maleate
生物活性 for 3-AQC
3-AQC is a competitive 5-HT3 antagonist, almost 100 times more potent than tropisetron, but with widely differing activity in various tissues.
技术数据 for 3-AQC
| 分子量 | 395.42 |
| 公式 | C16H17N5.C4H4O4 |
| 储存 | Desiccate at -20°C |
| CAS Number | 201216-42-4 |
| PubChem ID | 11567402 |
| InChI Key | UHLVYEOCPBNJNA-BTJKTKAUSA-N |
| Smiles | OC(=O)\C=C/C(O)=O.C=CCN1CCN(CC1)C1=NC2=CC=CC=C2N=C1C#N |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for 3-AQC
参考文献 for 3-AQC
参考文献是支持产品生物活性的出版物。
Buznikov et al (2005) The pre-nervous serotonergic system of developing sea urchin embryos and larvae: pharmacologic and immunocytochemical evidence. Neurochem.Res. 30 825 PMID: 16187217
Durk et al (2005) 5-Hydroxytryptamine modulates cytokine and chemokine production in LPS-primed human monocytes via stimulation of different 5-HTR subtypes. Int.Immunol. 17 599 PMID: 15802305
Monge et al (1993) Novel antagonists of 5-HT3 receptors. Synthesis and biological evaluation of piperazinylquinoxaline derivatives. J.Med.Chem. 36 2745 PMID: 8410988
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关键词: 3-AQC, 3-AQC supplier, 5-HT3, antagonists, Serotonin, Receptors, 0666, Tocris Bioscience
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该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
5-HT Receptors Scientific Review
Written by Nicholas M. Barnes and John F. Neumaier, this review summarizes the various serotonin receptor subtypes and their importance in mediating the role of serotonin in numerous physiological and pharmacological processes. Compounds available from Tocris are listed.