Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit Review3'-Fluorobenzylspiperone maleate
说明： D2-like receptor ligand
化学名： 8-[4-(4-Fluorophenyl)-4-oxobutyl]-(3-fluorobenzyl-1-phenyl)-1,3,8-triazaspiro[4,5]decan-4-one maleate
纯度： ≥98% (HPLC)
生物活性 for 3'-Fluorobenzylspiperone maleate
3'-Fluorobenzylspiperone maleate is a very potent and selective ligand for the D2 receptor (Ki = 0.023 nM). Compared with spiperone, displays a 2.5-fold greater affinity at D2 and a 12-fold lower affinity at 5-HT2 receptors.
技术数据 for 3'-Fluorobenzylspiperone maleate
| 分子量 | 619.67 |
| 公式 | C30H31F2N3O2.C4H4O4 |
| 储存 | Store at RT |
| 纯度 | ≥98% (HPLC) |
| CAS Number | 1135278-61-3 |
| PubChem ID | 24978532 |
| InChI Key | JURUFADWVGXLOY-BTJKTKAUSA-N |
| Smiles | OC(=O)\C=C/C(O)=O.FC1=CC=C(C=C1)C(=O)CCCN1CCC2(CC1)N(CN(CC1=CC=CC(F)=C1)C2=O)C1=CC=CC=C1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for 3'-Fluorobenzylspiperone maleate
参考文献 for 3'-Fluorobenzylspiperone maleate
参考文献是支持产品生物活性的出版物。
Mach et al (1992) Effect of N-alkylation on the affinities of analogues of spiperone for DA D2 and serotonin 5-HT2 receptors. J.Med.Chem. 35 423 PMID: 1531364
按标靶查看相关产品
按产品操作查看相关产品
关键词: 3'-Fluorobenzylspiperone maleate, 3'-Fluorobenzylspiperone maleate supplier, D2-like, ligand, Dopamine, Non-Selective, Receptors, dopaminergic, 3-Fluorobenzylspiperone, maleate, Non-selective, 0701, Tocris Bioscience
篇 3'-Fluorobenzylspiperone maleate 的引用文献
引用文献是使用了 Tocris 产品的出版物。
目前没有 3'-Fluorobenzylspiperone maleate 的引用文献。
3'-Fluorobenzylspiperone maleate 的评论
目前没有该产品的评论。 Be the first to review 3'-Fluorobenzylspiperone maleate and earn rewards!
Have you used 3'-Fluorobenzylspiperone maleate?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
Dopamine Receptors Scientific Review
Written by Phillip Strange and revised by Kim Neve in 2013, this review summarizes the history of the dopamine receptors and provides an overview of individual receptor subtype properties, their distribution and identifies ligands which act at each receptor subtype. Compounds available from Tocris are listed.
Parkinson's Disease Poster
Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.