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Submit Review5-Nonyloxytryptamine oxalate
说明： Selective 5-HT1B agonist
纯度： ≥99% (HPLC)
生物活性 for 5-Nonyloxytryptamine oxalate
5-HT1B selective agonist, several times more potent than sumatriptan and inactive as a 5-HT1A agonist (Ki at 5-HT1B = 1 nM, selectivity over 5-HT1A > 300-fold). Mimics polysialic acid activity, stimulates neuritogenesis, myelination and Schwann cell migration in vitro.
技术数据 for 5-Nonyloxytryptamine oxalate
| 分子量 | 392.49 |
| 公式 | C19H30N2O.C2H2O4 |
| 储存 | Store at RT |
| 纯度 | ≥99% (HPLC) |
| CAS Number | 157798-13-5 |
| PubChem ID | 10126593 |
| InChI Key | JORSCLBFSAAOFR-UHFFFAOYSA-N |
| Smiles | OC(=O)C(O)=O.CCCCCCCCCOC1=CC=C2NC=C(CCN)C2=C1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for 5-Nonyloxytryptamine oxalate
参考文献 for 5-Nonyloxytryptamine oxalate
参考文献是支持产品生物活性的出版物。
Glennon et al (1994) 5-(Nonyloxy)tryptamine: a novel high affinity-5-HT1Dβ serotonin receptor agonist. J.Med.Chem. 37 2828 PMID: 8071931
Glennon et al (1996) Binding of O-Alkyl derivatives of serotonin at human 5-HT1Dβ receptors. J.Med.Chem. 39 314 PMID: 8568822
Loers et al (2013) Nonyloxytryptamine mimics polysialic acid and modulates neuronal and glial functions in cell culture. J.Neurochem. 128 88 PMID: 23957498
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关键词: 5-Nonyloxytryptamine oxalate, 5-Nonyloxytryptamine oxalate supplier, Selective, 5-HT1B, agonists, Serotonin, Receptors, 0901, Tocris Bioscience
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