5-HT1B Receptors

Serotonin 5-HT1B receptors, previously known as 5-HT1D receptors, are primarily located in the basal ganglia, striatum, hippocampus and vascular smooth muscle. 5-HT1B receptors play a role in thermoregulation, respiration, appetite control, sexual behavior and aggression.

Products
Background
文献 (2)
Gene Data

5-HT1B Receptor Agonists

Cat. No. 产品名称/活性
0703 Anpirtoline hydrochloride
Highly potent 5-HT1B agonist; also 5-HT3 antagonist
0638 CGS 12066B dimaleate
5-HT1B agonist
1032 CP 93129 dihydrochloride
5-HT1B agonist
1317 CP 94253 hydrochloride
Potent and selective 5-HT1B agonist
3586 Sumatriptan succinate
5-HT1A, 5-HT1B and 5-HT1D agonist
4657 Zolmitriptan
Potent 5-HT1B/1D/1F agonist

5-HT1B Receptor Antagonists

Cat. No. 产品名称/活性
0993 Cyanopindolol hemifumarate
5-HT1A and 5-HT1B antagonist; also β-adrenergic antagonist
1477 GR 127935 hydrochloride
Potent and selective 5-HT1B and 5-HT1D antagonist
1054 GR 55562 dihydrochloride
5-HT1B antagonist
1242 SB 216641 hydrochloride
Selective h5-HT1B antagonist
1221 SB 224289 hydrochloride
Selective 5-HT1B antagonist

Serotonin 5-HT1B receptors, previously known as 5-HT1D receptors, are primarily located in the basal ganglia, striatum, hippocampus and vascular smooth muscle. 5-HT1B receptors play a role in thermoregulation, respiration, appetite control, sexual behavior and aggression.

External sources of pharmacological information for 5-HT1B Receptors :

Literature for 5-HT1B Receptors

Tocris offers the following scientific literature for 5-HT1B Receptors to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


5-HT Receptors Scientific Review

5-HT Receptors Scientific Review

Written by Nicholas M. Barnes and John F. Neumaier, this review summarizes the various serotonin receptor subtypes and their importance in mediating the role of serotonin in numerous physiological and pharmacological processes. Compounds available from Tocris are listed.

Parkinson's Disease Poster

Parkinson's Disease Poster

Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.

5-HT1B Receptor Gene Data

Species Gene Symbol Gene Accession No. Protein Accession No.
Human HTR1B NM_000863 P28222
Mouse Htr1b NM_010482 P28334
Rat Htr1b NM_022225 P28564