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6-Chloromelatonin

Cat. No. 0443 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

0443 has been discontinued.

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说明： Melatonin agonist
化学名： N-[2-(6-Chloro-5-methoxyindol-3-yl)ethyl]acetamide
纯度： ≥99% (HPLC)
说明书
引用文献
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生物活性 技术数据 说明书 参考文献

生物活性 for 6-Chloromelatonin

6-Chloromelatonin is a potent melatonin agonist (pKi values are 9.10 and 9.77 for human recombinant MT1 and MT2 receptors respectively). Displays higher affinity for binding to hamster brain membrane and chicken retina than melatonin.

技术数据 for 6-Chloromelatonin

分子量 266.73
公式 C13H15ClN2O2
储存 Desiccate at +4°C
纯度 ≥99% (HPLC)
CAS Number 63762-74-3
PubChem ID 1858
InChI Key LUINDDOUWHRIPW-UHFFFAOYSA-N
Smiles COC1=C(Cl)C=C2NC=C(CCNC(C)=O)C2=C1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for 6-Chloromelatonin

分析证书/产品说明书
化学品安全技术说明书

参考文献 for 6-Chloromelatonin

参考文献是支持产品生物活性的出版物。

Browning et al (2000) Pharmacological characterization of human recombinant melatonin mt1 and MT2 receptors. Br.J.Pharmacol. 129 877 PMID: 10696085

Dubocovich (1988) Luzindole (NO 774): A novel melatonin receptor antagonist. J.Pharmacol.Exp.Ther. 246 902 PMID: 2843633

Dubocovich (1995) Melatonin receptors: are there multiple subtypes? TiPS 16 50 PMID: 7762083

Duncan et al (1988) 2-[125I]Iodomelatonin binding sites in hamster brain membranes: pharmacological characteristics and regional distribution. Endocrinology 122 1825 PMID: 2834175

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关键词: 6-Chloromelatonin, 6-Chloromelatonin supplier, Melatonin, agonists, MT, Receptors, (MT), 0443, Tocris Bioscience

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