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Submit Review7-Hydroxy-DPAT hydrobromide
说明： Dopamine agonist (D3 ≥ D2 < > D4)
化学名： (±)-7-Hydroxy-2-dipropylaminotetralin hydrobromide
纯度： ≥99% (HPLC)
生物活性 for 7-Hydroxy-DPAT hydrobromide
7-Hydroxy-DPAT hydrobromide is a D3 dopamine receptor agonist (Ki values are ~ 1, 10, 650 and ~ 5000 nM for D3, D2, D4 and D1 receptors respectively).
8-Hydroxy Isomer also available.
技术数据 for 7-Hydroxy-DPAT hydrobromide
| 分子量 | 328.28 |
| 公式 | C16H25NO.HBr |
| 储存 | Desiccate at +4°C |
| 纯度 | ≥99% (HPLC) |
| CAS Number | 76135-30-3 |
| PubChem ID | 11957566 |
| InChI Key | ODNDMTWHRYECKX-UHFFFAOYSA-N |
| Smiles | Br.CCCN(CCC)C1CCC2=CC=C(O)C=C2C1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for 7-Hydroxy-DPAT hydrobromide
参考文献 for 7-Hydroxy-DPAT hydrobromide
参考文献是支持产品生物活性的出版物。
Daly and Waddington (1993) Behavioural effects of the D3 DA receptor agonist 7-OH-DPAT in relation to other D2-like agonists. Neuropharmacology 32 509 PMID: 8321432
Levesque (1996) Aminotetralin drugs and D3 receptor fuctions. Biochem.Pharmacol. 52 511 PMID: 8759022
Levesque et al (1992) Identification, characterization, and localization of the DA D3 receptor in rat brain using [3H]-7-hydroxy-N,N-di-n-propyl-2-aminotetralin. Proc.Natl.Acad.Sci.U.S.A. 89 8155 PMID: 1518841
Seeman and Van Tol (1994) DA receptor pharmacology. TiPS 15 264 PMID: 7940991
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关键词: 7-Hydroxy-DPAT hydrobromide, 7-Hydroxy-DPAT hydrobromide supplier, Dopamine, agonists, D3, Receptors, dopaminergic, 0706, Tocris Bioscience
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该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
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Written by Phillip Strange and revised by Kim Neve in 2013, this review summarizes the history of the dopamine receptors and provides an overview of individual receptor subtype properties, their distribution and identifies ligands which act at each receptor subtype. Compounds available from Tocris are listed.
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