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8-M-PDOT

Cat. No. 1035 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

1035 has been discontinued.

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说明： Melatonin agonist
化学名： 8-Methoxy-2-propionamidotetralin
纯度： ≥99% (HPLC)
说明书
引用文献
评论
生物活性 技术数据 说明书 参考文献

生物活性 for 8-M-PDOT

8-M-PDOT is a melatonin receptor agonist, 20-fold selective for the MT2 (vs MT1) subtype. At human recombinant MT1 and MT2 receptors, displays pKi values of 8.23 and 8.95 respectively.

技术数据 for 8-M-PDOT

分子量 233.31
公式 C14H19NO2
储存 Store at RT
纯度 ≥99% (HPLC)
CAS Number 134865-70-6
PubChem ID 5170952
InChI Key RVIGBTUDFAGRTQ-UHFFFAOYSA-N
Smiles CCC(=O)NC1CCC2=C(C1)C(OC)=CC=C2

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for 8-M-PDOT

参考文献是支持产品生物活性的出版物。

Browning et al (2000) Pharmacological characterization of human recombinant melatonin mt1 and MT2 receptors. Br.J.Pharmacol. 129 877 PMID: 10696085

Dubocovich et al (1997) Melatonin receptor antagonists that differentiate between the human Mel1a and Mel1b recombinant subtypes are used to assess the pharmacological profile of the rabbit retina ML1 presynaptic heteroceptor. Naunyn Schmiedebergs Arch.Pharmacol. 355 365 PMID: 9089668

Dubocovich et al (1995) Melatonin receptors: are there multiple subtypes? TiPS 16 50 PMID: 7762083

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关键词: 8-M-PDOT, 8-M-PDOT supplier, Melatonin, agonists, Receptors, MT, 8MPDOT, (MT), 1035, Tocris Bioscience

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