α,β-Methyleneadenosine 5'-triphosphate trisodium salt

Pricing Availability   Qty
说明: Non-selective P2 agonist
别名: α,β-meATP
化学名: α,β-Methyleneadenosine 5'-triphosphate trisodium salt
纯度: ≥98% (HPLC)
说明书
引用文献 (2)
评论 (1)
文献 (1)

生物活性

α,β-Methyleneadenosine 5'-triphosphate trisodium salt is a P2-purinoceptor agonist. Also shown to inhibit adenylate cyclase (Ki = 0.5 mM).

技术数据

分子量 571.15
公式 C11H15N5Na3O12P3
储存 Store at -20°C
纯度 ≥98% (HPLC)
CAS Number 1343364-54-4
PubChem ID 90488813
InChI Key CBAGKCWFSRTVER-MTQUBGKESA-K
Smiles O[C@@H]1[C@@H](COP(CP([O-])(OP([O-])(O)=O)=O)([O-])=O)O[C@@H](N3C2=NC=NC(N)=C2N=C3)[C@@H]1O.[Na+].[Na+].[Na+]

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
water 57.12 100

制备储备液

以下数据基于产品分子量 571.15。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 1.75 mL 8.75 mL 17.51 mL
5 mM 0.35 mL 1.75 mL 3.5 mL
10 mM 0.18 mL 0.88 mL 1.75 mL
50 mM 0.04 mL 0.18 mL 0.35 mL

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产品说明书

分析证书/产品说明书
选择另一批次:

参考文献

参考文献是支持产品生物活性的出版物。

Krug et al (1973) α,β-Methylene-adenosine 5'-triphosphate. J.Biol.Chem. 248 1203 PMID: 4686923

Burnstock and Kennedy (1985) Is there a basis for distinguishing two types of P2-purinoceptor? Gen.Pharmacol 16 433 PMID: 2996968


If you know of a relevant reference for α,β-Methyleneadenosine 5'-triphosphate trisodium salt, please let us know.

按产品操作查看相关产品

查看全部 Purinergic (P2Y) Receptor Agonists

关键词: alpha,beta-Methyleneadenosine 5'-triphosphate trisodium salt, alpha,beta-Methyleneadenosine 5'-triphosphate trisodium salt supplier, P2, agonists, P2-purinoceptor, P2Y, Receptors, Purinergic, P2X, purinoceptors, α, β-Methyleneadenosines, alpha,beta-Methyleneadenosines, 5-triphosphate, trisodium, salt, a,b-Methyleneadenosine, a,b-meATP, 3209, Tocris Bioscience

2 篇 α,β-Methyleneadenosine 5'-triphosphate trisodium salt 的引用文献

引用文献是使用了 Tocris 产品的出版物。 α,β-Methyleneadenosine 5'-triphosphate trisodium salt 的部分引用包括:

Palygin et al (2018) Characterization of purinergic receptor expression in ARPKD cystic epithelia. Purinergic Signal 14 485 PMID: 30417216

Haanes and Edvinsson (2014) Expression and characterization of purinergic receptors in rat middle meningeal artery-potential role in migraine. PLoS One 9 e108782 PMID: 25265286


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α,β-Methyleneadenosine 5'-triphosphate trisodium salt 的评论

平均评分: 4 (Based on 1 Review.)

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P2 agonist.
By Anonymous on 05/17/2018
种属: Human

P2X1 and P2X3 agonist, the product works as expected.


该领域的文献

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P2X and P2Y Receptors Scientific Review

P2X and P2Y Receptors Scientific Review

Written by Kenneth Jacobson, this review provides an overview of the different subtypes and structures of the P2 receptor families, as well as the pharmacological probes used to study them; compounds available from Tocris are listed.