Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit Reviewα-helical CRF 9-41
说明： CRF antagonist
别名： α-helical-Corticotropin-Releasing Factor 9-41
纯度： ≥95% (HPLC)
生物活性 for α-helical CRF 9-41
α-helical CRF 9-41 is a corticotropin-releasing factor receptor antagonist (Ki values are 17, 5 and 0.97 at human CRF1, rat CRF2α and mouse CRF2β receptors respectively).
许可信息
Sold with the permission of the SALK Institute
技术数据 for α-helical CRF 9-41
| 分子量 | 3827 |
| 公式 | C166H274N46O53S2 |
| 序列 |
DLTFHLLREMLEMAKAEQEAEQAALNRLLLEEA (Modifications: Ala-33 = C-terminal amide) |
| 储存 | Store at -20°C |
| 纯度 | ≥95% (HPLC) |
| CAS Number | 90880-23-2 |
| PubChem ID | 44593730 |
| InChI Key | PNGVJHODDQMQKT-GVKLFNHCSA-N |
| Smiles | [H]N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(N)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for α-helical CRF 9-41
参考文献 for α-helical CRF 9-41
参考文献是支持产品生物活性的出版物。
Kask et al (1997) Alpha-helical(9-41) revents anxiogenic-like effect of NPY Y1 receptor antagonist BIBP3226. NeuroReport 8 3645 PMID: 9427342
Perrin and Vale (1999) Corticotropin releasing factor receptors and their ligand family. Ann.N.Y.Acad.Sci. 885 312 PMID: 10816663
Swerdlow et al (1989) Potentiation of acoustic startle by corticotropin-releasing factor (CRF) and by fear are both reversed by α-helical CRF (9-41). Neuropsychopharmacology 2 285 PMID: 2610824
按产品操作查看相关产品
关键词: alpha-helical CRF 9-41, alpha-helical CRF 9-41 supplier, CRF, receptor, antagonists, Corticotropin-Releasing, Factor, Non-Selective, Receptors, α-helical, alpha-helical, 9-41, a-helical, CRF9-41, a-helical-Corticotropin-Releasing, Factor9-41, Non-selective, 1184, Tocris Bioscience
2 篇 α-helical CRF 9-41 的引用文献
引用文献是使用了 Tocris 产品的出版物。 α-helical CRF 9-41 的部分引用包括：
Wang et al (2014) Involvement of CRH and hCG in the induction of aromatase by cortisol in human placental syncytiotrophoblasts. Placenta 35 30 PMID: 24239159
Jia et al (2013) Role of nesfatin-1 in a rat model of visceral hypersensitivity. J Immunol 19 3487 PMID: 23801843
α-helical CRF 9-41 的评论
目前没有该产品的评论。 Be the first to review α-helical CRF 9-41 and earn rewards!
Have you used α-helical CRF 9-41?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
Depression Poster
Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.