Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewABT 751
说明： Inhibitor of microtubule polymerization; antimitotic and antitumor
化学名： N-[2-[(4-Hydroxyphenyl)amino]-3-pyridinyl]-4-methoxybenzenesulfonamide
纯度： ≥98% (HPLC)
生物活性 for ABT 751
ABT 751 is an antimitotic agent, inhibits microtubule polymerization. Binds to β-tubulin on the colchine site; blocks cell cycle at G2M phase and induces apoptosis. Exhibits antitumor activity. Also displays activity in cell lines resistant to vincristine, doxorubicin and cisplatin. Orally bioavailable.
技术数据 for ABT 751
| 分子量 | 371.41 |
| 公式 | C18H17N3O4S |
| 储存 | Store at +4°C |
| 纯度 | ≥98% (HPLC) |
| CAS Number | 141430-65-1 |
| PubChem ID | 3035714 |
| InChI Key | URCVCIZFVQDVPM-UHFFFAOYSA-N |
| Smiles | OC(C=C2)=CC=C2NC1=NC=CC=C1NS(C3=CC=C(OC)C=C3)(=O)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for ABT 751
参考文献 for ABT 751
参考文献是支持产品生物活性的出版物。
Hande et al (2006) The pharmacokinetics and safety of ABT-751, a novel, orally bioavailable sulfonamide antimitotic agent: results of a phase 1 study. Clin.Cancer Res. 12 2834 PMID: 16675578
关键词: ABT 751, ABT 751 supplier, ABT751, microtubule, antitumor, antimitotic, beta, tubulin, b-tubulin, blocks, cell, cycle, G2M, proapoptotic, Microtubules, Cell, Cycle, Inhibitors, 4138, Tocris Bioscience
ABT 751 的评论
目前没有该产品的评论。 Be the first to review ABT 751 and earn rewards!
Have you used ABT 751?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
Cell Cycle and DNA Damage Research Product Guide
This product guide provides a review of the cell cycle and DNA damage research area and lists over 150 products, including research tools for:
- Cell Cycle and Mitosis
- DNA Damage Repair
- Targeted Protein Degradation
- Ubiquitin Proteasome Pathway
- Chemotherapy Targets