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Acarbose

Cat. No. 2673 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
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说明： Glucosidase α inhibitor (intestinal)
别名： Bay-g 5421
化学名： O-4,6-Dideoxy-4-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-α-D-glucopyranosyl-(1-4)-O-α-D-glucopyranosyl-(1-4)-D-Glucose
说明书
引用文献
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生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for Acarbose

Acarbose is an inhibitor of intestinal α-glucosidase (IC50 = 11 nM). Antidiabetic; inhibits the hydrolysis of complex carbohydrates.

化合物库 for Acarbose

Acarbose is also offered as part of the Tocriscreen FDA-Approved Drugs. 了解 Tocris 化合物库的更多信息。

技术数据 for Acarbose

分子量 645.25
公式 C25H43NO18
储存 Desiccate at RT
CAS Number 56180-94-0
PubChem ID 444254
InChI Key XUFXOAAUWZOOIT-SXARVLRPSA-N
Smiles C[C@H]1O[C@H](O[C@@H]2[C@@H](CO)O[C@H](O[C@@H]3[C@@H](CO)O[C@@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1N[C@H]1C=C(CO)[C@@H](O)[C@H](O)[C@H]1O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Acarbose

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
water 64.52 100
DMSO 64.52 100

制备储备液 for Acarbose

以下数据基于产品分子量 645.25。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 1.55 mL 7.75 mL 15.5 mL
5 mM 0.31 mL 1.55 mL 3.1 mL
10 mM 0.15 mL 0.77 mL 1.55 mL
50 mM 0.03 mL 0.15 mL 0.31 mL

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产品说明书 for Acarbose

分析证书/产品说明书
选择另一批次：
化学品安全技术说明书

参考文献 for Acarbose

参考文献是支持产品生物活性的出版物。

Krause et al (1982) Inhibition of disaccharide digestion in rat intestine by the alpha-glucosidase inhibitor aca. (BAY g 5421). Digestion 23 232 PMID: 6754513

Balfour and McTavish (1993) Acarbose: an update of its pharmacology and therapeutic use in diabetes mellitus. Drugs 46 1025 PMID: 7510610

Oki et al (2000) Evaluation of alpha-glucosidase inhibition by using an immobilized assay system. Biol.Pharm.Bull. 23 1084 PMID: 10993209

If you know of a relevant reference for Acarbose, please let us know.

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关键词: Acarbose, Acarbose supplier, Glucosidase, alpha, inhibitors, inhibits, intestinal, Glycosylases, Carbohydrate, Metabolism, Bay-g5421, Bay-g, 5421, 2673, Tocris Bioscience

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